Clin2
NCT07782138Possibly a fitNot yet recruiting

Natural killer cell transplant for Mooren's ulcer

Cornea Disease

Part of Eyes & vision clinical trials.

This trial tests a new treatment using natural killer (NK) cells, which are immune cells that may help heal the eye. It is for people with a specific type of corneal ulcer called Mooren's ulcer that has not improved with standard treatments.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
6 people
Ages
18 years to 85 years
Study type
Interventional

Who can take part

  • You are between 18 and 85 years old.
  • You have a Mooren's ulcer that covers no more than half of the cornea and is not too deep.
  • You have symptoms like eye pain, sensitivity to light, tearing, or feeling like something is in your eye.
  • Standard treatments have not worked well for you.
  • You do not have severe complications like a hole in the cornea or infection inside the eye.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07435142Recruiting
Urine-derived cells for corneal eye disease

This trial tests if using special cells from your own urine can help repair the inner layer of your cornea (the clear front part of your eye). It may be an option if you have damage to these cells and have already had at least one cornea transplant.

Jinan, Shandong
NCT05705024Recruiting· Phase 2
Eye drops/treatment to heal stubborn cornea surface damage

This Phase 2 trial tests a locally delivered cell-based treatment (allogeneic mesenchymal stromal cells) to help heal long-lasting damage to the eye’s clear surface (the cornea). It may help if your cornea epithelium (surface layer) won’t improve even after standard non-surgical treatments.

Chicago, Illinois
NCT06753916Recruiting· Phase 2
Trial of a new treatment for high-risk cornea transplants

This study tests a new approach to help prevent cornea transplant failure in people with high-risk conditions, such as blood vessels growing into the cornea. It aims to see if this treatment can improve transplant success.

Irvine, California
NCT06700655Not yet recruiting· Phase 1/Phase 2
Stem cell transplant for corneal injury repair

This study tests a new treatment that uses your own stem cells to repair a damaged cornea after a chemical burn. It may help reduce scarring and improve vision.

NCT07247201Not yet recruiting· Phase 1/Phase 2
Natural killer cell therapy with standard treatment for advanced nasopharyngeal cancer

This study tests whether adding natural killer (NK) cells, which are immune cells that can attack cancer, to the usual chemotherapy and radiation treatment helps people with advanced nasopharyngeal cancer. It aims to improve treatment outcomes for patients with high-risk disease.

Singapore
NCT07526389Not yet recruiting
Artificial cornea study for severe corneal blindness

This study tests an artificial cornea (a small plastic implant) to see if it can safely improve vision in people who are blind from corneal damage and cannot have a regular cornea transplant. It aims to help those with no other good treatment options.

Hear when a new Cornea Disease trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.