Natural killer cell treatment for Mooren's ulcer
Part of Eyes & vision clinical trials.
This trial tests a new treatment using special immune cells (natural killer cells) from a healthy donor to help heal a painful type of eye ulcer (Mooren's ulcer). It may help people whose ulcer has not improved with standard care.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a Mooren's ulcer (a painful, shallow eye ulcer) that has not healed with usual treatments.
- The ulcer covers no more than half of the cornea's edge and is not too deep (less than two-thirds of the cornea's thickness).
- You have symptoms like eye pain, sensitivity to light, tearing, or feeling like something is in your eye.
- Your eye pressure is normal (10–21 mmHg), and you do not have other serious eye problems in the affected or other eye.
- You are between 18 and 85 years old.
- You are generally healthy: no serious heart, liver, kidney, or blood problems; no active infections, cancer, or recent surgery; if diabetic, your blood sugar is well controlled (HbA1C below 8.5%).
- You are not pregnant or breastfeeding, and you are willing to use effective birth control if there is any chance of pregnancy.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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