Clin2
NCT07783191Possibly a fitNot yet recruiting

Rapid fluid replacement for very high blood sodium

Hypernatremia

Part of Hormones & metabolism clinical trials.

This study tests a fast method of giving fluids by IV to quickly correct very high blood sodium levels. The goal is to restore balance safely without causing complications.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
80 people
Ages
21 years and older
Study type
Interventional

Who can take part

  • You must be 21 years old or older.
  • You must be in the emergency room, a medical ward, or intensive care unit.
  • Your blood sodium level must be 155 or higher (your care team can check this).
  • Your weight must be between about 88 and 265 pounds.
  • You cannot be pregnant or breastfeeding.
  • You cannot have certain serious conditions like recent heart attack, stroke, or kidney failure.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06872645Recruiting
Sodium-restricted diet for PD patients with high blood pressure

This study tests a new way to manage sodium (salt) for people on peritoneal dialysis. It aims to see if reducing sodium intake without water can help control blood pressure and improve health.

New Haven, Connecticut
NCT06498856Not yet recruiting
Saltwater test for low blood sodium

This study tests a simple procedure called a saline infusion test, where you get a mild saltwater solution through an IV, to see how well your body handles low sodium. Your sodium levels will be monitored to understand why your sodium is low and help guide your treatment.

NCT05692726Recruiting
Tracking salt and fluid balance in low-sodium treatment

This observational study measures how body fluid and electrolytes change in adults with low blood sodium caused by low “tonicity” (not diluted by high sugar or other causes). It may help clinicians better understand which treatment approaches keep sodium levels safer and more stable.

Cologne
NCT06020495Recruiting· Phase 3
DDAVP to prevent sodium overcorrection in severe low sodium

This trial tests a medication called DDAVP to prevent the sodium level from rising too quickly when treating severe low sodium in ICU patients. It is for those with dangerously low sodium and neurological symptoms, but without certain other medical conditions.

Amiens
NCT07576036Enrolling by invitation
Study of severe low sodium and brain safety during treatment

This is a retrospective study (meaning researchers look back at medical records) of patients who had very low sodium levels in their blood when admitted to the hospital. Researchers want to understand the link between how quickly doctors correct low sodium and a rare brain condition called osmotic demyelination syndrome.

Pittsburgh, Pennsylvania
NCT07756801Not yet recruiting· Phase 4
Comparing treatments for fluid overload in cardiogenic shock

This trial tests a treatment to help remove extra fluid from the body when the heart is too weak to pump effectively. It may help people in intensive care who have fluid buildup and are at risk of kidney problems.

Ottawa, Ontario

Hear when a new Hypernatremia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.