Tapering semaglutide for weight-loss maintenance
Part of Hormones & metabolism clinical trials.
This study tests whether slowly reducing the dose of the weight-loss medication semaglutide can help keep weight off after losing at least 10% of body weight. It compares two ways of tapering the dose to see which works better for maintaining weight loss.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 64 years old.
- You have been taking semaglutide (like Wegovy or Ozempic) weekly for weight loss.
- You have lost at least 10% of your starting weight, OR lost 5-10% and your BMI is now below 25.
- You have been on a 1.7 mg dose for at least 12 weeks, with your weight holding steady (less than 5% change).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This early-stage study tests a small implant placed under the skin that releases a weight management medicine (semaglutide) slowly over time. The goal is to see how safe it is and how your body handles it.
This trial tests whether adding a plant-based supplement (called 20E) to the weight-loss medication semaglutide can improve weight loss and muscle health. You would take the supplement as capsules alongside your regular semaglutide treatment.
This trial compares different ways to keep weight off after you've lost weight using a GLP-1 medication, like semaglutide or tirzepatide. It tests reducing your GLP-1 dose and adding other weight loss medications to help maintain your progress.
This study tests whether a medication called semaglutide, which is used for weight loss, works better for people who also have binge eating. It aims to find the best treatment based on brain and behavior differences.
This study tests whether a low dose of semaglutide (a once-weekly injection) can help obese adults without diabetes lose weight. Semaglutide works by reducing appetite and helping your body use food differently.
This study looks at two ways to stop taking semaglutide (a weight-loss medication), either by lowering the dose gradually or stopping all at once, for people who have used it after weight-loss surgery. It aims to see which way helps keep weight off more stably.
Hear when a new Obesity & Overweight trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.