Testing a natural compound for weight loss with semaglutide
Treatments studied
Part of Brain & nervous system, Hormones & metabolism clinical trials.
This trial tests if adding a natural compound called 20E (20-hydroxyecdysone) to the weight-loss drug semaglutide can help people with obesity lose more weight and keep muscle. You would take both medications and follow a diet and exercise plan.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are starting treatment with semaglutide for weight loss.
- Your body mass index (BMI) is 30 or higher, or 27 or higher with weight-related health issues like high blood pressure or sleep apnea.
- You are willing to eat at least 1 gram of protein per kilogram of your body weight every day (for example, 70 grams if you weigh 70 kg).
- You are willing to exercise at least 150 minutes per week at a moderate to vigorous level.
- Your weight has been stable (within about 11 pounds) for the past 3 months.
- You are not currently taking certain medications, including other weight-loss drugs, antidepressants, or steroids, and you do not have diabetes, gallbladder disease, or serious liver or kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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