Clin2
NCT07788586Possibly a fitNot yet recruiting

Shortening treatment for uncomplicated candidemia

CandidemiaInvasive Candidiasis

Part of Infections clinical trials.

This trial tests whether a shorter course of the antifungal drug caspofungin (7 days instead of the usual 14) is just as effective for people with uncomplicated candidemia, a bloodstream infection caused by Candida yeast. If you've already had 7 days of caspofungin and your blood is clear of Candida, you might be able to stop treatment sooner.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 4
Enrollment
420 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 years or older.
  • You have been diagnosed with candidemia (a Candida infection in the blood) and have already received 7 days of treatment with caspofungin.
  • Your blood tests show the Candida infection is gone, and you have no signs of complicated infection (like in the heart, brain, or bones).
  • Any central line (like a PICC or port) has been removed or replaced within 48 hours of starting caspofungin.
  • You are not pregnant or breastfeeding, and if you could become pregnant, you agree to use effective birth control during the study.
  • You do not have severe liver disease, a weakened immune system (low white blood cell count), or certain other conditions that might make a shorter treatment less safe.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06859671Not yet recruiting· Phase 3
Shorter treatment for candidemia (yeast infection in the blood)

This trial compares a shorter course of antifungal medicine to a longer one for people who have candidemia (a yeast infection in the blood). It looks at whether treating for a shorter time is just as safe and effective, which could mean fewer side effects and a quicker recovery.

NCT06907992Not yet recruiting
Comparing 7-day vs 14-day antifungal treatment for uncomplicated bloodstream yeast infection

This trial compares two lengths of antifungal treatment for a bloodstream yeast infection that has not spread: 7 days versus the standard 14 days. The goal is to see if a shorter course works just as well with fewer side effects.

Augusta, Georgia
NCT05763251Recruiting
Shorter antifungal treatment for yeast bloodstream infection in children

This trial compares shorter vs longer treatment for children with an uncomplicated yeast (Candida) bloodstream infection once blood cultures are clear. It may help reduce medicine exposure while keeping the infection under control.

Birmingham, Alabama
NCT05421858Recruiting· Phase 3
Study drug for adults with bloodstream or deep Candida infection

This Phase 3 trial tests fosmanogepix to treat adults with candidemia (Candida in the bloodstream) and/or invasive candidiasis (a deep Candida infection). It looks at whether the medicine is effective and safe, and whether it helps the infection improve when doctors also manage the infection source.

Birmingham, Alabama
NCT06456151Recruiting
Candida infection in critically ill patients study

This study looks at patients in the intensive care unit who have a new infection with Candida (a type of fungus) despite taking strong antibiotics. It aims to better understand and diagnose these serious infections.

Ostrava, Moravian-Silesian Region
NCT07295314Not yet recruiting· Early Phase 1
Antifungal medicines and their effect on gut bacteria

This study tests whether a short course of antifungal medicines changes the natural bacteria in your gut. It is a small early study, so the main goal is to see if the drug has an effect and if it's safe, which could one day help treat gut-related conditions.

Amsterdam

Hear when a new Candidemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.