Early rheumatic heart disease screening study in children across Africa
Part of Heart & circulation, Infections clinical trials.
This study checks children aged 5–8 for early signs of rheumatic heart disease, a heart problem that can follow a strep throat infection. It aims to see how common it is in different parts of Africa to help prepare for a future vaccine. Children with a normal heart ultrasound at the start may join.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 5 to 8 years old at the time you join the study.
- You live in the area where the study is taking place.
- A parent or guardian must agree to let you take part.
- If you are old enough, you will be asked to agree to join (called 'assent').
- Your heart ultrasound (echocardiogram) must be normal at the first visit.
- You have never had rheumatic fever or rheumatic heart disease, and you don't have any other heart problems (except a small patent foramen ovale or atrial septal defect).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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