Custom dosing of anti-thymocyte globulin for stem cell transplant
Treatments studied
This trial tests whether giving anti-thymocyte globulin (ATG) based on a person's own body chemistry can reduce side effects and improve outcomes in stem cell transplants. It is for people with certain blood cancers who are in their first or second remission.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a blood cancer that is in its first or second complete remission (no signs of cancer).
- You have a donor who is a matched sibling, matched unrelated, or half-matched (haploidentical).
- You are between 14 and 65 years old.
- Your liver and kidney function are within acceptable limits.
- You are physically active enough (ECOG 0-2) and have no uncontrolled infections or severe mental health issues.
- You are not pregnant and are willing to sign a consent form.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests a personalized approach to using ATG (a medicine that reduces immune rejection) in patients receiving stem cell transplants from unrelated donors for blood cancers. The goal is to improve transplant success while reducing side effects by tailoring ATG doses to individual patients.
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This trial tests a personalized dosing method for a medicine called ATG, which helps prevent your body from rejecting a donor stem cell transplant. It is for people with blood cancers who need a transplant from an unrelated donor.
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This trial tests if a two-step course of a drug called ATG (anti-thymocyte globulin) can help prevent a serious side effect called graft-versus-host disease (GVHD) after a donor stem cell transplant. It is for people with certain blood cancers who are receiving a reduced-intensity transplant.
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