Clin2
NCT07791732Possibly a fitNot yet recruiting

Maintenance therapy for recurrent ovarian cancer after second-line treatment

Fallopian Tube CancerPrimary Peritoneal CancerHigh-Grade Serous Ovarian CancerEndometrioid Epithelial Ovarian

Treatments studied

Part of Cancer, Hormones & metabolism, Women’s health & pregnancy clinical trials.

This study tests a new investigational drug, raludotatug deruxtecan (R-DXd), given alone or with another drug called bevacizumab, as maintenance treatment after second-line platinum-based chemotherapy for recurrent ovarian cancer. The goal is to keep the cancer from growing longer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 3
Enrollment
600 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are an adult assigned female at birth.
  • You have high-grade serous or endometrioid ovarian, primary peritoneal, or fallopian tube cancer.
  • You have a documented BRCA or HRD test result.
  • You have received two prior lines of platinum-based chemotherapy, and your disease responded or remained stable after the most recent one.
  • You are not planning to have a PARP inhibitor as your next maintenance treatment.
  • You are physically active (able to do light work) and have acceptable organ function.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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