Clin2
NCT07793435Possibly a fitNot yet recruiting

ADI-212 for advanced prostate cancer that has stopped responding to hormone therapy

Prostate Cancer Metastatic

Treatments studied

Part of Cancer clinical trials.

This trial tests a new medicine called ADI-212 for men with advanced prostate cancer that has spread and is no longer responding to hormone therapy. The medicine targets a protein on cancer cells called PSMA, which may help the immune system attack the cancer.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
12 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You have prostate cancer that has spread to other parts of the body.
  • Your cancer is still growing despite hormone therapy (and you are currently on hormone therapy).
  • You have tried at least two prior hormone treatments, and you may have had one chemotherapy (taxane) treatment.
  • Your cancer shows up on a PSMA PET scan.
  • You are in generally good health (able to do light activity) and have adequate organ function.
  • You have not had certain prior treatments (like CAR-T or gene therapy) and are willing to follow safety monitoring.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT06320067Recruiting· Phase 3
Testing treatments for metastatic hormone-sensitive prostate cancer

This trial tests two newer treatments—targeted radiation (SABR) or a special radioactive drug (Lu-177 PSMA-617)—added to standard hormone therapy for men with prostate cancer that has spread. The goal is to see if these additional treatments help control the cancer better.

Barnsley
NCT05720130Recruiting· Phase 1/Phase 2
Study drug for advanced prostate cancer found on PSMA scans

This trial tests [212Pb]Pb-ADVC001, a radiotherapy-like cancer treatment, in people with advanced prostate cancer that shows up on a special PSMA scan. It aims to find the safest dose and see whether it helps shrink or control metastatic cancer.

Brisbane, Queensland
NCT06492122Recruiting· Phase 1
Study of a radioactive drug for advanced prostate cancer

This trial tests a new radioactive treatment, [225Ac]Ac-FL-020, for men with metastatic castration-resistant prostate cancer (mCRPC) that has gotten worse despite other treatments. It's for those who have had at least one prior hormone therapy or chemotherapy.

Duarte, California
NCT07611110Recruiting· Phase 3
AZD2265 vs standard care for advanced prostate cancer

This trial tests a new cancer-fighting drug called AZD2265 against standard treatment for men with advanced prostate cancer that has spread and stopped responding to hormone therapy. You may qualify if your cancer previously responded to PSMA-targeted radiation treatments but is now growing again.

Dothan, Alabama
NCT06801236Recruiting· Phase 1
A new drug for advanced prostate cancer that has stopped responding to treatment

This early-phase trial tests a new study drug called ACE-232 for men with advanced prostate cancer that has stopped responding to standard hormone therapy and chemotherapy. It aims to see if the drug is safe and may help slow the cancer.

La Jolla, California
NCT04633252Recruiting· Phase 1/Phase 2
Study drug plus docetaxel and abiraterone for advanced prostate cancer

This trial tests a new targeted cancer drug (PDS01ADC) combined with standard treatments docetaxel and abiraterone for men with advanced prostate cancer that has spread. The goal is to see if the combination is safe and whether it can control cancer better than current approaches.

Bethesda, Maryland

Hear when a new Prostate Cancer Metastatic trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.