Mouth tissue graft to repair a narrowed ureter
Part of Kidney & urinary clinical trials.
This trial tests using a small piece of tissue from the inside of your cheek to widen a narrowed part of the tube that carries urine from your kidney to your bladder. This may help restore normal urine flow and avoid more invasive surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years or older.
- You have a narrowing (stricture) in the upper or middle part of the ureter that is longer than 2 cm.
- The narrowing can be new or has come back after previous treatment (surgery or endoscopic procedure).
- You do not have cancer in the urinary tract or active pelvic/retroperitoneal cancer.
- You do not have an active urinary tract infection at the time of surgery.
- You do not have bleeding problems or other conditions that make surgery unsafe.
- You do not have active mouth disease, oral submucous fibrosis, or have had grafting from both cheeks before.
- You are not pregnant.
- Your affected kidney must still have some function (more than 15% of total kidney function).
- Your ureter is not completely blocked, and a guidewire can still pass through it.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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