Early study of a new drug for overweight or obese adults
Part of Hormones & metabolism clinical trials.
This study tests an experimental drug called IBI3042 in healthy people who are normal weight, overweight, or obese. It is an early-stage trial looking at how safe and tolerable the drug is, and how it affects the body, which could eventually lead to a treatment for weight loss.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 55 years old.
- Your body mass index (BMI) is within a certain range depending on the part of the study: for Part A, BMI between 20 and 28; for Part B, BMI between 24 and 40.
- If you are female and can become pregnant, or male with a partner who can become pregnant, you must agree to use highly effective birth control during the study and for 90 days after the last dose.
- You have not been diagnosed with diabetes or have abnormal blood sugar levels.
- You have no personal or family history of a rare thyroid cancer (medullary thyroid carcinoma) or a condition called multiple endocrine neoplasia syndrome type 2.
- You have no history of pancreatitis (inflammation of the pancreas) or high pancreatic enzyme levels.
- You have not taken any medications that affect digestion, appetite, or how your body absorbs drugs within the past 3 months.
- You have no significant health problems such as heart, kidney, liver, or psychiatric conditions that could make the study risky.
- You have not had cancer (except certain skin cancers) within the last 5 years.
- You have not used any prescription or over-the-counter medications, supplements, or herbal remedies within 2 weeks before the study starts.
- You have not participated in another clinical trial within the past 3 months.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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