Naloxone for heart stoppage in the hospital
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests whether giving naloxone (a medicine that blocks the effects of opioid drugs) during CPR can improve survival after a cardiac arrest in the hospital. It may help by reversing any opioid-related causes of the cardiac arrest, potentially giving you a better chance of recovery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 years of age or older.
- Your heart must have stopped while you were already in the hospital (called an in-hospital cardiac arrest).
- During CPR, you must have received at least one dose of adrenaline, a medicine that helps restart the heart.
- You cannot have a 'do-not-resuscitate' order, meaning you have chosen not to be revived.
- You cannot be pregnant or have previously said you do not want to join this trial.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
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This trial tests whether care from a specialist team helps people recover better after a cardiac arrest outside the hospital. If you were revived and brought to the emergency department with a pulse, you might be eligible.
This trial tests whether giving naloxone, a medicine that reverses the effects of opioids, during a cardiac arrest outside the hospital can help save lives. It is for adults whose cardiac arrest may have been caused by opioid use.
This trial tests whether a combination of three medications (epinephrine, vasopressin, and a steroid) given by paramedics before arriving at the hospital can improve survival for adults who have a cardiac arrest outside of a hospital. It is only for patients who are treated by specially trained paramedics and meet specific medical criteria.
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This study tests emergency treatments for people who have had a cardiac arrest (heart stops beating) outside the hospital. It looks at two groups: people whose hearts stop despite CPR efforts, and people whose hearts have restarted. The goal is to see if these treatments can help patients survive and recover better.
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