Study of HRS-4729 injection in healthy people and those with kidney problems
Part of Digestive system, Hormones & metabolism clinical trials.
This study is testing a new injectable medicine (HRS-4729) to see how the body processes it in people with healthy kidneys and in those with kidney problems. If you join, you will receive a single dose and have your blood and urine checked over time to measure the drug levels.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be between 18 and 65 years old, and your weight must be in a healthy range (body mass index between 19 and 40).
- You must have either healthy kidneys or stable kidney disease (no sudden changes in the last month).
- If you are a woman who can have children, you must use reliable birth control and have a negative pregnancy test before the study. Men must agree to use contraception or not father a child during and for 2 months after the study.
- You must not have a history of certain cancers, pancreatic problems, or thyroid conditions (like medullary thyroid carcinoma or MEN2).
- You must not have had major surgery in the last 6 months, or participated in another drug trial within the last 3 months.
- You must be willing to avoid caffeine (tea, coffee, cola, chocolate, energy drinks), alcohol, and strenuous exercise for 48 hours before the study dose.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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