Strolimus-coated balloon for blocked coronary arteries
Part of Heart & circulation, Pain clinical trials.
This study tests a balloon coated with a drug that may help keep arteries open after they've been cleared, especially for people with a narrowing inside a previously placed stent or in a small heart artery. It's a first-time-in-humans study to check if the treatment is safe and works.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 21 or older.
- You have symptoms of heart disease, like chest pain or shortness of breath, or a test shows your heart isn't getting enough blood.
- You need a procedure to open a blocked heart artery (called angioplasty).
- You are able to take blood-thinning medicines like aspirin plus one of these: clopidogrel, prasugrel, or ticagrelor.
- The blocked artery is a small blood vessel (about the width of a coffee stir stick) or you have a re-narrowing inside a previous stent.
- If you're a woman who could have children, you agree to use effective birth control from screening until 12 months after the procedure.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a special balloon coated with a drug (sirolimus) to treat blockages in small heart arteries. If the balloon is successful, it may help keep the artery open without needing a permanent stent.
This trial tests whether a special drug-coated balloon (“MagicTouch”) can treat re-narrowing inside a previously placed stent. It may help patients whose stent has become blocked again, by improving blood flow and reducing repeat narrowing.
This study follows adults with blocked heart arteries who are treated using a special type of balloon (drug-coated balloon) during a procedure. It aims to track real-world outcomes to better understand how well this treatment works for people with new blockages or previously treated vessel narrowing.
This study tests a drug-coated balloon (DCB) that releases two medicines (sirolimus and paclitaxel) to open blocked small heart arteries. It may help people with stable chest pain or recent, controlled heart events who have a narrowed small vessel.
This trial tests a new stent (a small mesh tube) to open narrowed heart arteries and improve blood flow. It may help people with multiple blocked arteries who are having a procedure to widen them.
This study looks at how to treat blocked heart arteries that have narrowed again after a prior drug-eluting stent. It compares using another drug-eluting stent versus a drug-coated balloon, chosen based on an imaging scan inside the artery (OCT), to reduce repeat narrowing.
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