Clin2
NCT07828483Possibly a fitNot yet recruiting

Focused ultrasound for depression after brain injury in veterans

Post-traumatic Brain Injury DepressionVeteran Health

Part of Brain & nervous system, Injuries & trauma, Mental health clinical trials.

This study tests a non-invasive treatment called low-intensity focused ultrasound (LIFU) for depression that started after a mild or moderate traumatic brain injury (TBI) in veterans. It aims to see if this treatment can safely improve mood without surgery.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
25 people
Ages
22 years to 55 years
Study type
Interventional

Who can take part

  • You are a veteran aged 22 to 55.
  • You have had a mild or moderate brain injury (not a penetrating wound) that was confirmed by medical records.
  • Your depression began at least 3 months after the brain injury and has lasted less than 2 years.
  • You have tried at least one antidepressant at a stable dose for 6 weeks, but it hasn't worked well enough.
  • You are not currently using any illegal substances and are not pregnant.
  • You are able to attend regular visits and have access to ongoing psychiatric care.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT05426967Recruiting
Brain stimulation for depression after mild traumatic brain injury

This trial studies a noninvasive brain treatment (rTMS) to reduce depression symptoms in people with past mild traumatic brain injury from military service. It may help by changing brain activity, while also requiring stable mental health care and regular follow-up.

Palo Alto, California
NCT07164105Recruiting
Using low-intensity ultrasound to treat PTSD in healthcare workers

This study tests whether a new non-invasive brain treatment called low-intensity focused ultrasound (LIFU) can help reduce PTSD symptoms in healthcare workers. It aims to find out how the treatment works and if it is safe and effective.

Tulsa, Oklahoma
NCT06820138Recruiting· Phase 2
Focused ultrasound treatment for PTSD in veterans

This study tests a non-invasive treatment called focused ultrasound for veterans with PTSD. Focused ultrasound uses sound waves to target specific brain areas without surgery. It aims to reduce PTSD symptoms like distress and anxiety.

Providence, Rhode Island
NCT07220655Recruiting
How focused ultrasound affects thinking and brain activity

This trial uses low-intensity focused ultrasound (LIFU) and brain scans to see how it affects thinking. It may help researchers find new ways to treat brain conditions.

Minneapolis, Minnesota
NCT06906211Recruiting
Ultrasound for chronic back pain in veterans

This trial tests if a gentle ultrasound treatment to a specific part of the brain can help veterans with chronic back pain. It aims to see if targeting the insula can reduce pain that spreads to other areas of the body.

Washington D.C., District of Columbia
NCT07166289Recruiting
Ultrasound treatment for tough depression

This study uses focused ultrasound to stimulate brain circuits in people with treatment-resistant depression. It aims to see if this can help when other treatments haven't worked.

Tulsa, Oklahoma

Hear when a new Post-traumatic Brain Injury Depression trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.