Clin2
NCT07829055Possibly a fitEnrolling by invitation

Effects of mental tasks on breathing in chronic opioid users

Opiod Use DisorderObstructive Sleep Apnea

Part of Brain & nervous system, Lungs & breathing clinical trials.

This study looks at how doing mental tasks affects breathing in people who take opioids daily for chronic pain, compared to those with sleep apnea and healthy people. It may help understand how opioids affect breathing and improve safety.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
40 people
Ages
45 years to 65 years
Study type
Observational

Who can take part

  • You are 18 or older
  • You can give consent and follow instructions in English
  • If you take opioids: you take a prescribed opioid daily for chronic pain for at least 3 months, at a dose of 20 or more morphine milligram equivalents per day, and your dose has been stable for at least 2 weeks
  • If you have sleep apnea: you have a diagnosis with AHI of 15 or more (from a sleep study)
  • If you are healthy: you do not take chronic opioids and you have no history of sleep apnea
  • Your BMI is between 20 and 35, you are not pregnant, and you have no serious health conditions
  • You do not have significant other diseases like kidney disease, heart failure, cirrhosis, severe lung disease, or conditions affecting breathing muscles

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07678918Not yet recruiting
Thinking and memory in people with sleep apnea

This study looks at how obstructive sleep apnea (OSA) affects thinking, memory, and quality of life. It involves people with OSA and a comparison group without it, to better understand the impact of the condition.

NCT07386769Recruiting
Brain activity during social interaction in opioid use

This study looks at how the brain works during social interactions in people who use opioids regularly. It may help researchers understand how opioid use affects the way you connect with others.

La Jolla, California
NCT05607381Recruiting
Meditation program study for opioid-treated chronic low back pain

This trial studies how meditation may change brain activity and help people with long-lasting low back pain who are already taking prescription opioids. The goal is to understand the “neural” (brain) effects of meditation to improve pain treatment.

La Jolla, California
NCT05589753Recruiting· Phase 1/Phase 2
Testing treatment for sleep breathing problems in people on opioids

This trial studies a treatment approach for sleep-disordered breathing (breathing problems during sleep) in Veterans who take prescription opioids. It may help doctors learn safer ways to manage sleep breathing issues that can be made worse by opioid use.

Detroit, Michigan
NCT06854211Not yet recruiting· Early Phase 1
Effects of morphine on breathing during sleep

This study tests how a single dose of morphine affects breathing during sleep in people both with and without sleep apnea. It aims to understand if opioids are riskier for people with sleep apnea.

Boston, Massachusetts
NCT06800703Recruiting
Opioid use, pain, and the brain

This study uses brain scans (MRI) to understand how pain affects people with opioid use disorder or regular opioid use, compared to healthy volunteers. It aims to find better ways to treat both pain and opioid addiction.

New Haven, Connecticut

Hear when a new Opiod Use Disorder trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.