Opioids' effect on breathing during sleep
Part of Brain & nervous system, Lungs & breathing clinical trials.
This study tests how a single dose of morphine affects breathing during sleep in healthy people and those with sleep apnea. It aims to understand the risks of opioids for people with breathing disorders.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older and able to have a sleep study done in the lab.
- You must either be healthy (with no sleep apnea) or have sleep apnea (AHI > 10).
- You cannot be taking any medications that affect breathing or interact with morphine, such as certain antidepressants, sedatives, or other opioids.
- You cannot have serious health conditions like heart disease, kidney or liver problems, asthma, COPD, or a history of seizures or head injury.
- You cannot be pregnant or breastfeeding, or have a history of substance abuse.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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