Clin2
NCT07831187Possibly a fitNot yet recruiting

Combination treatment for recurrent glioblastoma

Glioblastoma

Treatments studied

Part of Cancer clinical trials.

This trial tests a new combination of two drugs, entacapone and bevacizumab, for people whose glioblastoma (a type of brain tumor) has returned after initial treatment. The goal is to see if this combination can help control the tumor and improve outcomes.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 1/Phase 2
Enrollment
96 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You are 18 or older.
  • You have been diagnosed with a type of brain tumor called glioblastoma that has come back after your first treatment.
  • You have completed your initial radiation therapy with the chemotherapy drug temozolomide.
  • You have not had treatment with bevacizumab or similar drugs before.
  • You are generally well enough to carry out daily activities (Karnofsky score of 70 or higher).
  • You have not had surgery for this recurrence, or you have decided not to have surgery.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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