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Study of oral RXC008 for Crohn's disease strictures

Strictures Due to Crohn's Disease

Treatments studied

Part of Digestive system clinical trials.

This trial tests an oral medicine called RXC008 to see if it can help people with Crohn's disease who have narrowed areas in their small intestine (strictures). It aims to reduce symptoms and improve quality of life without needing surgery or dilation.

Summary written for real people, not researchers, by Clin2.

Phase
Phase 2
Enrollment
180 people
Ages
18 years and older
Study type
Interventional

Who can take part

  • You must be between 18 and 80 years old (BMI between 16 and 40).
  • You have symptoms from a narrowed area in your small intestine caused by Crohn's disease.
  • You have up to two narrowed areas, and the main one is reachable by a scope through the colon.
  • Your Crohn's treatment has been stable for at least 12 weeks (for biologics) and you don't plan to change it during the study.
  • You have not had balloon dilation or intestinal surgery in the past 6 months, and you're not expected to need it within the next 6 months.
  • You do not have active fistulas, abscesses, or other serious complications of Crohn's disease.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

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