Study of a new drug for tenosynovial giant cell tumor (TGCT)
Part of Bones, joints & muscles, Cancer clinical trials.
This study tests an experimental drug (DCC-3014) for people with TGCT, a non-cancerous joint tumor. The drug may help reduce pain and improve joint movement without the risks of surgery.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have a confirmed TGCT tumor in a single joint.
- You have at least moderate pain or stiffness in that joint.
- Surgery to remove the tumor would likely cause severe problems or worsen your joint function.
- You have not had another cancer (except certain skin cancers) in the last 5 years.
- You do not have an abnormal heart rhythm or long QT syndrome.
- You do not have active liver disease.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests a new drug called pimicotinib for people in Japan with tenosynovial giant cell tumor (TGCT) that cannot be removed by surgery. It aims to see if the drug can help with pain and stiffness caused by the tumor.
This Phase 1 study tests how safe a new drug (ABSK-021) is, what side effects it causes, and how the body processes it in people with advanced solid tumors. You may be eligible if your cancer has grown despite standard treatments or if no standard treatment exists.
This trial tests whether taking a new drug (pimicotinib) before surgery can shrink the tumor and make surgery more effective, compared to having surgery right away. It is for people with a type of benign but aggressive joint tumor called diffuse TGCT.
This trial tests a new targeted therapy drug, DCC-3009, for people with advanced GIST that has a specific gene mutation (KIT or PDGFRA). It's for those who have already tried other targeted treatments and need a new option.
This study tests an experimental medication (JMT103) for people with giant cell tumor of bone that cannot be safely removed with surgery. The drug may help shrink the tumor or slow its growth, providing an option when surgery is too risky.
This trial tests a new drug called TGW101 for people with certain advanced solid tumors that have not responded to standard treatments. The goal is to see if it is safe and may help shrink tumors.
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