Testing a new drug for advanced GIST with specific gene changes
Part of Cancer, Digestive system clinical trials.
This trial tests a new targeted therapy drug, DCC-3009, for people with advanced GIST that has a specific gene mutation (KIT or PDGFRA). It's for those who have already tried other targeted treatments and need a new option.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your GIST has spread or cannot be removed with surgery and has a KIT or PDGFRA gene mutation.
- You have already tried at least one targeted therapy (like imatinib) and it either stopped working or caused side effects.
- You have at least one tumor that can be measured on a scan.
- You are able to do most daily activities on your own (ambulatory).
- You have not had cancer treatment in the last 2 weeks or major surgery in the last month.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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