Chemical treatment compared with observation for small eardrum holes
Part of Ear, nose & throat, Injuries & trauma clinical trials.
This study compares two ways to help a small hole in the eardrum close: using a chemical (silver nitrate) to encourage healing, versus just watching and waiting. If you have a small, dry hole in one eardrum that has not healed on its own, this trial may help you find a treatment that could improve your hearing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You have a small hole (less than 4 mm) in one eardrum only.
- Your ear has been dry (no fluid or discharge) for at least 4 weeks.
- You have some hearing loss in the affected ear that is due to the eardrum hole, not nerve damage.
- You do not have diabetes or an allergy to silver nitrate.
- You are willing to have the chemical treatment applied to your eardrum and come for weekly check-ups.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a surgery that uses a small piece of cartilage to close large holes in the eardrum of children. It aims to improve hearing and reduce the risk of the hole coming back.
This study looks at Tympanoseal for people who still have a childhood ear tube or a small eardrum hole. It may help protect the ear and improve healing, while researchers compare outcomes using a standardized approach.
This trial tests a new way to fix a hole in the eardrum using a curved piece of cartilage. It aims to improve the success of the surgery for a specific type of eardrum hole.
This trial tests a special gel applied during common ear surgeries to see if it helps healing and improves hearing. It may be an option for people having surgery to fix a perforated eardrum, repair ear bones, or treat chronic ear infections.
This trial tests whether adding an extra layer of connective tissue (fascia) during eardrum repair improves results for people with large holes in their eardrum. It may help reduce the chance of the hole coming back and improve hearing.
This study compares two treatments applied during a procedure to repair a hole in the eardrum. It aims to find which treatment helps the eardrum heal better.
Hear when a new Tympanic Membrane Perforation trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.