Clin2
NCT07834125Possibly a fitNot yet recruiting

Study of unexplained high liver enzymes

Cryptogenic Hypertransaminasemia

Part of Cancer, Digestive system clinical trials.

This study is looking at people with unexplained high liver enzymes (ALT or AST) that have persisted for at least 6 months. Researchers want to understand what might be causing these elevations and are comparing them to people with normal liver tests.

Summary written for real people, not researchers, by Clin2.

Phase
N/A
Enrollment
30 people
Ages
18 years and older
Study type
Observational

Who can take part

  • You are 18 years or older.
  • Your liver enzymes (ALT or AST) have been higher than normal for at least 6 months, and doctors haven't found a cause yet.
  • You have not been diagnosed with fatty liver disease (MASLD), alcohol-related liver disease, viral hepatitis, or other known genetic liver conditions.
  • You do not have celiac disease, thyroid problems, muscle disease, active infection, or cancer.
  • You haven't taken antibiotics or probiotics in the last 3 months, and you're not on immune-suppressing drugs.
  • You are not pregnant.

View the official record on ClinicalTrials.gov

Quick eligibility check

Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.

Similar studies

Other trials that look related to this one.

NCT07249112Recruiting
Genomic study of metabolic fatty liver disease

This study aims to understand the genetic factors behind metabolic fatty liver disease (MASLD) by comparing patients with advanced liver scarring or liver cancer to healthy blood donors. It may help doctors better predict and treat the disease in the future.

Milan, Milano
NCT04371042Recruiting
Study of liver disease and genes in people with fatty liver

This study collects information about metabolic and unexplained (cryptogenic) liver disease and looks at “omics” tests, which are lab tests that measure patterns in blood or tissue to learn what drives the disease. It may help researchers better understand fatty liver and related serious complications, like liver scarring and liver cancer.

Roma, Rome/lazio/italy
NCT06813508Recruiting
Liver cancer and transplant study for MASLD patients

This study looks at factors that predict liver cancer and the need for a liver transplant in people with a liver condition called MASLD (metabolic dysfunction-associated steatotic liver disease). The goal is to better understand the disease and improve care.

Bologna, Bologna
NCT07877272Recruiting
Better liver testing for high-risk fatty liver disease

This study tests a more detailed way to examine the liver in people with fatty liver disease who also have other health risks. The doctors want to see if this extra testing helps decide whether you need treatment.

Münster
NCT06653140Not yet recruiting
Finding the cause for unexplained acute hepatitis

This study looks for better ways to find and diagnose hepatitis when the cause is not clear. If you join, doctors will monitor your condition and test samples to try to identify what's causing your liver inflammation.

Beijing, Beijing Municipality
NCT06986447Enrolling by invitation
Non-invasive tests for serious liver disease

This study is testing whether advanced imaging and other non-invasive methods can properly identify people with significant liver scarring due to metabolic liver disease or alcohol-related liver disease. It may help find better ways to track liver health without repeated needle biopsies.

Chandler, Arizona

Hear when a new Cryptogenic Hypertransaminasemia trial opens

We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.