Nerve block for frequent dangerous heart rhythms
Part of Heart & circulation clinical trials.
This trial tests whether a numbing injection around a nerve cluster in the neck (called a stellate ganglion block) can stop dangerous rapid heart rhythms (electrical storm) more effectively than usual care. If you are having repeated episodes that need defibrillator shocks, this may help calm your heart rhythm and reduce further shocks.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older.
- You have had more than 3 episodes of a very fast heart rhythm (ventricular tachycardia or fibrillation) that required a shock from a defibrillator in the last 12 hours, with at least one in the last 3 hours.
- You have any type of structural heart disease (a heart condition that affects the heart's structure), acute or chronic coronary disease, or CPVT.
- You do not have Brugada syndrome or early repolarization syndrome.
- You have not had a heart transplant, surgical sympathetic denervation, or ablation of the stellate ganglion before.
- You are not currently on IV anti-arrhythmic drugs (unless certain conditions are met), and you are not pregnant, breastfeeding, or allergic to the study drugs.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial looks at a procedure called a stellate ganglion block to calm dangerous, repeated heart rhythm attacks that haven’t improved with standard medicines. It may help reduce how often and how long these episodes last while you’re in the hospital.
This trial tests whether injecting numbing medicine around neck nerves (stellate ganglion block) can calm dangerous heart rhythms called electrical storm. It's for people with heart disease whose abnormal rhythms keep happening despite usual medications.
This study tests a procedure called sympathetic ablation, which targets the nerves that contribute to dangerous heart rhythms in people with implanted defibrillators. The goal is to reduce the number of shocks from your device and improve your quality of life.
This trial tests a non-invasive nerve stimulation treatment (using a small device on the ear) to reduce dangerous heart rhythm problems. It is for people with frequent premature heartbeats (PVCs) or with an implanted defibrillator who have had repeated episodes of a fast heart rhythm (VT).
This trial tests a nerve block in the neck to calm the heart's electrical system and stop repeated dangerous heart rhythms (electrical storm). It may help people who are having many episodes of ventricular tachycardia or ventricular fibrillation in a short time.
This trial studies how a type of nerve stimulation affects the heart’s electrical signals during a procedure to treat a dangerous fast heart rhythm (ventricular tachycardia). It may help doctors better understand safety and effects during planned ablation.
Hear when a new Electrical Storm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.