Adding DHEA hormone to antidepressants for difficult depression
Part of Mental health clinical trials.
This study tests whether adding a natural hormone called DHEA to your regular antidepressant can help improve depression symptoms. DHEA is a supplement that may boost the effectiveness of standard antidepressants for people with hard-to-treat depression.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 75 years old.
- You have been diagnosed with major depression that hasn't responded to at least one antidepressant treatment.
- Your depression severity score is at least 20 on a standard scale.
- You are currently taking a standard antidepressant at a stable dose for at least 4 weeks.
- You have not tried more than three different antidepressants for the current episode.
- You are not taking certain other psychiatric medications (like antipsychotics or lithium).
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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