Pain relief after hip replacement: comparing two medications
Treatments studied
Part of Pain clinical trials.
This study tests two medications added to a numbing injection (nerve block) given before hip replacement surgery to see which one controls pain better after the operation. The goal is to find an approach that reduces pain and helps you recover more comfortably.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 18 and 60 years old.
- You are scheduled for a total hip replacement on one side, and the anesthesia will be spinal (numbing from the waist down).
- You are in generally good health (classified as ASA I or II by your anesthesiologist).
- You do not have an infection or skin problem at the injection site.
- You do not have a bleeding disorder, and you are not allergic to the study drugs.
- You do not have a slow heart rate or significant heart rhythm problem.
- You are not currently taking daily strong pain medications (opioids) or have chronic pain requiring regular painkillers.
- You are able to communicate and describe your pain level.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This study tests a medicine called dexmedetomidine to see how well it relieves pain during hip replacement surgery done with spinal anesthesia. It may help improve pain control during and after the procedure.
This study compares two types of nerve blocks for pain relief after hip replacement surgery. It aims to find which method reduces pain and improves recovery.
This study compares two pain-relieving medicines added to a numbing injection around the hip. The goal is to find which one works better and lasts longer after your hip surgery.
This study compares two ways to manage pain after hip replacement surgery: a nerve block near the hip (PENG block) versus a small dose of morphine given through the spinal anesthesia. The goal is to see which method helps patients recover better and have less pain in the first days after surgery.
This study compares two ways to manage pain after hip replacement surgery: one uses a spinal injection with morphine, and the other uses a nerve block near the hip. The nerve block may include an extra medicine called dexamethasone to see if it improves pain relief.
This study compares two types of spinal anesthesia (numbing medicine injected near the spine) to see which one provides better pain relief and a shorter recovery for hip replacement surgery. If you qualify, you would receive one of the two medications during your surgery and help doctors learn which is more effective for getting you home the same day.
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