Comparing two drug combinations for older adults with a new type of AML
Part of Blood & lymphatic, Cancer clinical trials.
This study compares two chemotherapy combinations for older adults newly diagnosed with acute myeloid leukemia (AML) that has certain gene changes (NPM1 or IDH1/IDH2). The goal is to see if the new combination works better and has fewer side effects than the standard one.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are 18 years or older
- You have been newly diagnosed with acute myeloid leukemia (AML), but not a subtype called acute promyelocytic leukemia
- Your leukemia has a change in the NPM1 gene or the IDH1 or IDH2 genes
- You have not received any previous chemotherapy for AML, except a drug called hydroxyurea
- You are generally able to care for yourself (ECOG score 0-3)
- Your liver, kidneys, and heart are working well enough
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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