Treating chest pain in hypertrophic cardiomyopathy with a coronary sinus reducer
Part of Heart & circulation, Pain clinical trials.
This study tests a device called a coronary sinus reducer for people with hypertrophic cardiomyopathy (a condition where the heart muscle is thickened) who still have symptoms like chest pain. The device is placed in a vein of the heart to improve blood flow and reduce symptoms.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You have hypertrophic cardiomyopathy without obstruction (no blockage of blood flow out of the heart)
- You still have symptoms like chest pain or shortness of breath despite taking current medications
- A special heart MRI (CMR) shows areas of reduced blood flow in at least two segments of the heart
- You are 18 years or older
- You do not have severe kidney problems, a very weak heart pump, or a device like an ICD that would interfere with MRI
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new, less invasive procedure called SESAME that uses a special catheter to carefully trim the thickened heart muscle wall (septum) to improve blood flow and reduce symptoms. It's for people with hypertrophic cardiomyopathy or those at risk of obstruction during mitral valve replacement.
This trial uses a special PET scan to see if the drug Mavacamten (Camzyos) helps improve blood flow to the heart muscle in people with hypertrophic obstructive cardiomyopathy (HOCM) who have chest pain or shortness of breath. If you already take Mavacamten as part of your usual care, the study will compare your PET scan results before and after treatment.
This trial tests a device placed in a heart vein to improve symptoms in people whose heart pumps normally but still causes shortness of breath and fatigue. The device may help relieve pressure in the heart and improve daily life.
This trial tests a small device called a coronary sinus reducer that is placed in a vein of the heart to improve blood flow and reduce chest pain in people who still have angina despite medications and cannot have stents or bypass surgery. The procedure is done through a small tube in the groin or arm.
This study tests a device called the sinus reducer for people with long-lasting chest pain that hasn't improved with medication or other procedures. It may help if you have limited options for treatment.
This trial tests whether a small pressure-reducing device placed in a heart vein (the coronary sinus) can reduce symptoms in people with ongoing chest pain from tiny blood vessel problems. It is for angina that has not improved despite standard heart medicines, and only if special heart tests show reversible reduced blood flow.
Hear when a new Hypertrophic Cardiomyopathy trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.