Comparing two cell treatments for children needing a stem cell transplant
This study tests two ways to prepare donated blood cells for children who need a stem cell transplant but don't have a perfectly matched sibling donor. The aim is to reduce side effects and improve outcomes.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 0 and 18 years old.
- You need a stem cell transplant but don't have a fully matched sibling donor.
- You have a half-matched (haploidentical) donor, such as a parent.
- Your vital organs (like heart, lungs, liver, kidneys) are working well enough for the strong chemotherapy and radiation given before the transplant.
- You are generally able to be up and about (performance status score of at least 50).
- You are not pregnant or breastfeeding, and you do not have HIV.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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