Comparing two antibiotic combinations for children after appendectomy
Treatments studied
Part of Digestive system, Infections clinical trials.
This trial tests two different antibiotic regimens given after surgery for a ruptured appendix in children. The goal is to see which one works better to prevent infections and help children recover.
Summary written for real people, not researchers, by Clin2.
Who can take part
- Your child had their appendix removed using small incisions (laparoscopic surgery).
- The surgeon found that the appendix had a hole or other signs of rupture during the operation.
- Your child is not being treated with antibiotics alone (without surgery) for the rupture.
- The surgery was not done later as a planned second step after an initial abscess treatment.
- The surgery was completed without needing a large open cut.
- Your child does not have a known allergy to penicillin or cephalosporin antibiotics, and does not have kidney problems.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a new recovery plan designed to help children go home faster and feel better sooner after laparoscopic appendix surgery (a minimally invasive operation). The plan focuses on early movement, eating, and pain control without heavy pain medications.
This study compares two common ways to treat a simple (uncomplicated) appendix problem in children: using antibiotics versus having surgery to remove the appendix. The goal is to see which approach works better and helps children recover faster.
This study tests a faster recovery plan for children who had surgery for complicated appendicitis. It aims to see if children can leave the hospital sooner and recover well at home with oral antibiotics instead of staying longer in the hospital.
This study looks at why some people with uncomplicated appendicitis get better with antibiotics alone, while others still need surgery. If you join, researchers will track your treatment to find patterns that help predict success, aiming to help more patients avoid surgery in the future.
This trial tests whether taking antibiotics alone can treat acute uncomplicated appendicitis, compared with a placebo. If antibiotics work, it may help some people avoid surgery or reduce treatment intensity.
This trial tests whether rinsing the belly with antibiotics during appendix removal surgery can lower the chance of a pocket of infection (abscess) forming afterward. It may help people with a more severe type of appendicitis called complicated appendicitis.
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