Guaifenesin for mucus in chronic bronchitis
Part of Infections, Lungs & breathing clinical trials.
This study tests whether the over-the-counter medicine guaifenesin (also known as Mucinex) can make mucus easier to cough up in people with chronic bronchitis. It aims to see if this treatment helps clear mucus and improve breathing.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You are between 40 and 75 years old.
- You have chronic bronchitis with a daily cough that produces mucus, lasting at least 3 months for 2 years in a row.
- You have not had a recent flare-up of your breathing problems in the last month.
- You have not used guaifenesin products (like Mucinex) in the past month.
- You are not currently using certain other mucus-thinning medications or steroid pills.
- You have a history of smoking for at least 10 years, but you have not smoked in the past year.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This trial tests whether inhaling a saltwater solution (hypertonic saline) twice a day for 12 weeks can help people with bronchiectasis who have a chronic cough and have had flare-ups in the past. It aims to see if this treatment reduces mucus and improves quality of life.
This study tests an inhaled medicine (GDC-6988) to see if it is safe and helps clear mucus from the lungs in people with mucus-related lung diseases like chronic bronchitis, COPD, or bronchiectasis. You may qualify if your lung function is fairly stable and you produce daily mucus.
This trial tests an investigational tablet for people with chronic lung diseases like bronchiectasis, COPD, or asthma who produce at least 10 mL of sputum (mucus coughed up from the lungs) each day. The goal is to see if the drug safely reduces excess airway mucus.
This study is looking at how mucus builds up in the airways of people with asthma, COPD, or chronic cough. Researchers will also compare findings to healthy volunteers. The goal is to better understand these conditions and find new ways to help.
This study tests a new medicine, AG2001, to see if it safely helps adults with acute bronchitis (a sudden chest cold with cough and phlegm). If you have a recent, bothersome cough and sputum, this trial might offer a new treatment option.
This study is testing a new device called Simeox 200 to help clear mucus from your lungs. If you have bronchiectasis and produce a lot of mucus daily, this device might make it easier to breathe and reduce lung infections.
Hear when a new Bronchitis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.