Clinical trials
Adolescence clinical trials
Below are recruiting adolescence clinical trials, each written for real people, not researchers. We’re tracking 954 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06379789RecruitingPhase 1/Phase 2
Gene therapy for severe hemophilia B
This trial tests a new gene therapy (REGV131-LNP1265) that aims to let your body produce its own factor IX, reducing or stopping the need for regular infusions. It is for children and adults with severe hemophilia B who are already using factor IX replacement therapy.
Los Angeles, CaliforniaAges 2 years+ - NCT05609916Recruiting
CBT therapy to help kids stop OCD medicine
This trial studies whether adding structured talk therapy (CBT) can help some children with obsessive-compulsive disorder (OCD) reduce and potentially stop their OCD medicine. It’s designed for kids who are still having meaningful symptoms despite being on an OCD medication long enough.
Houston, TexasAges 7–17 - NCT06012240RecruitingPhase 3
Testing Upadacitinib for Severe Alopecia Areata
This study tests an oral tablet called upadacitinib for people with severe alopecia areata who have lost at least half of their scalp hair. It aims to see if the drug can safely help hair regrow.
Birmingham, AlabamaAges 12–63 - NCT06067893Enrolling by invitationPhase 4
Low dose sedation medicine for pain after scoliosis surgery
This trial tests a low dose of a sedative medicine, dexmedetomidine, given during and after spine surgery to see if it helps with pain. It is for teens and adults with scoliosis having back fusion surgery.
Kansas City, MissouriAges 10–21 - NCT05875363Recruiting
Mental health study for youth in the justice system
This study looks at brain development and mental health challenges in young people who have been involved with the police. It aims to understand these issues better so that we can find ways to support them.
TaipeiAges 10–18 - NCT05857813Recruiting
Social skills group training for teens with autism
This trial tests a structured social skills training group for adolescents with autism spectrum disorder (ASD) to improve day-to-day social functioning. It involves both the teen and a Chinese-speaking caregiver who helps support the training at home.
TaipeiAges 11–20 - NCT07196748RecruitingPhase 3
Icotrokinra for adults and teens with moderate to severe ulcerative colitis
This trial tests a new oral medication, icotrokinra, for people with moderately to severely active ulcerative colitis. It may be an option if you have not responded well enough to standard treatments or newer advanced therapies.
Chandler, ArizonaAges 12 years+ - NCT07559136RecruitingPhase 1
Safety study of HRS9531 injection for teen obesity
This study tests whether a new injectable medication called HRS9531 is safe and well-tolerated in teenagers aged 12–17 with obesity. Researchers will monitor how your body handles the medication and whether it affects your weight.
Wuhan, HubeiAges 12–18 - NCT06991673Enrolling by invitation
Surgery support app for teens
This study tests a new support app for teens having surgery. It's designed to help with pain and recovery. Both the teen and a caregiver (who provides at least half the care) are needed.
Ann Arbor, MichiganAges 12–99 - NCT07706764RecruitingPhase 3
Testing a new treatment for teens with long-term hypoparathyroidism
This study tests a new medicine called palopegteriparatide for teenagers with long-term hypoparathyroidism (low parathyroid hormone). The medicine is given as a daily injection and aims to help control calcium levels.
BronAges 12–18 - NCT07727694Recruiting
Access to new cancer drugs for children and young adults
This trial helps children, teens, and young adults with cancer get early access to promising new drugs that are not yet fully approved for their age group. It collects information on how these drugs work in real-world use.
AntwerpAges birth–25 years - NCT07089121RecruitingPhase 1/Phase 2
Descartes-08 for young people with autoimmune diseases
This trial tests a new therapy called Descartes-08 for children, teens, and young adults with autoimmune conditions like lupus, myasthenia gravis, or dermatomyositis. It aims to see if it can help control moderate disease that hasn't responded well enough to other treatments.
Washington D.C., District of ColumbiaAges 12 years+ - NCT07675161Recruiting
MiniMed wearable device study for children with diabetes
This study tests a small wearable device that helps manage diabetes. It is designed for children and teens ages 7 to 17 who use insulin, and aims to see how well the device fits and works in daily life.
Sacramento, CaliforniaAges 7–17 - NCT07049575RecruitingPhase 1
Ruxolitinib cream study for hidradenitis suppurativa
This study tests a cream called ruxolitinib for people with hidradenitis suppurativa (HS). The goal is to see how much of the cream is absorbed when it's applied to a large area of the body.
Phoenix, ArizonaAges 12–75 - NCT07476183RecruitingPhase 1
Testing APR-2020 for RPS19-deficient Diamond-Blackfan Anemia
This trial is testing a new treatment called APR-2020 for children and young adults with a specific type of Diamond-Blackfan Anemia (caused by a change in the RPS19 gene). The goal is to see if this treatment is safe, tolerable, and can help reduce the need for blood transfusions.
Stanford, CaliforniaAges 2–25 - NCT07717892RecruitingPhase 3
Solriamfetol for teens with ADHD
This study tests a new medicine, solriamfetol, to see if it helps teenagers with ADHD. The medicine is taken as a tablet and may improve focus and reduce symptoms.
Dothan, AlabamaAges 12–17 - NCT06967389Recruiting
Helping kids with severe obesity reduce heart risks
This trial tests whether semaglutide can lower heart disease risks in children with extreme obesity. It aims to improve weight and heart health over time.
Lexington, KentuckyAges 12–17 - NCT07713251Recruiting
Computer skills training for teens seeking alcohol help
This study tests a computer-based program called Path180 to help teenagers ages 13-19 reduce their alcohol use. If you are already seeing a counselor or in treatment for alcohol or mental health, this program might add extra support.
Providence, Rhode IslandAges 13–19 - NCT07715786Recruiting
Blood flow restriction with hamstring exercise in teen athletes
This study tests if adding blood flow restriction (using a cuff that limits blood flow) to a standard hamstring exercise helps elite teen athletes build strength and prevent injury. You would perform the Nordic Hamstring Exercise twice, once with and once without the cuff, so researchers can compare the effects.
AdanaAges 14–18 - NCT07424404RecruitingPhase 3
Long-term safety trial for teens with schizophrenia or autism irritability
This trial looks at the long-term safety of KarXT, a medication for schizophrenia, and KarX-EC for irritability related to autism in teenagers. It is for teens who have already completed the main part of a previous study without serious side effects.
Dothan, AlabamaAges 5–17 - NCT06672939RecruitingPhase 3
Orforglipron for Weight Loss in Teens
This study tests a once-daily pill (orforglipron) to help adolescents with obesity or overweight plus related health problems lose weight. It offers a new option for teens who have struggled to lose weight with diet and exercise alone.
Ventura, CaliforniaAges 12–17 - NCT07288567RecruitingPhase 3
KarXT for teens with schizophrenia
This trial tests if a new medicine, KarXT, can safely and effectively treat schizophrenia in adolescents. It may help teenagers who have active symptoms like hallucinations or disorganized thinking.
Anaheim, CaliforniaAges 13–17 - NCT06147973Recruiting
Healthy lifestyle program for teen girls
This study tests a healthy lifestyle program that helps teen girls accept their bodies and make positive changes. It aims to see if this approach can improve weight-related health and well-being.
Philadelphia, PennsylvaniaAges 14–19 - NCT07711730Recruiting
Telehealth support for kids with limb-girdle muscular dystrophy
This study tests an online program to help children and teens with limb-girdle muscular dystrophy improve their thinking, social skills, and emotional well-being. You join from home using a computer with a camera and internet.
Bilbao, BiscayAges 7–17
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Common questions
- Are there clinical trials for adolescence?
- Yes. Clin2 currently lists 954 recruiting adolescence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.