Clinical trials
Adolescence clinical trials
Below are recruiting adolescence clinical trials, each written for real people, not researchers. We’re tracking 952 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05329441Recruiting
Testing an anti-depression medicine for threat-related brain changes in teens
This trial studies how fluoxetine or escitalopram (anti-depression medicines) may affect brain systems involved in feeling threatened and staying anxious when you have depression. It also uses brain scanning and blood tests to measure these changes.
Los Angeles, CaliforniaAges 14–21 - NCT06365892Recruiting
Open-label placebo for pain after scoliosis surgery
This trial tests whether taking a placebo pill that you know is a placebo (open-label placebo) can help reduce pain after spinal fusion surgery for scoliosis. It compares the placebo to standard care in adolescents aged 11-17.
San Francisco, CaliforniaAges 10–18 - NCT06341634Enrolling by invitation
Suicide ideation surveillance in teens
This study follows adolescents aged 11 to 16 to better understand and track suicidal thoughts. It may help improve care for teens with or without these thoughts.
Santiago de Compostela, A CoruñaAges 11–16 - NCT06310434Enrolling by invitation
Understanding compassion in teens and young adults facing end-of-life
This study looks at how teenagers and young adults understand compassion and human connection when facing the end of life. It may help improve how schools and families support young people during difficult times.
Murcia, MUAges 12–23 - NCT06072677Recruiting
Mood and testosterone in young teens
This study looks at how mood changes during puberty in young people aged 11 to 14. It tests whether using a mindfulness app (Healthy Minds) can help teens who have been through stress or feel down.
Chapel Hill, North CarolinaAges 11–14 - NCT07736456Enrolling by invitation
Exercise program for teens with mild to moderate scoliosis
This study tests a 16-week corrective exercise program for adolescents with idiopathic scoliosis. It aims to see if these exercises can improve spinal curves and posture without surgery or bracing.
Pristina, KosovoAges 10–18 - NCT07702812Recruiting
Schroth and Pilates for teens with scoliosis
This study compares Schroth and Pilates exercises for teenagers with mild to moderate idiopathic scoliosis (curved spine). It aims to see which therapy works best for improving posture and reducing curve progression.
AnkaraAges 10–18 - NCT06916208Recruiting
Capsinoid supplement study for obese teens
This study tests whether a supplement called capsinoid can help activate brown fat in teenagers with obesity. Brown fat is a type of body fat that burns calories, so this could be a new way to help with weight management.
Palavas-les-FlotsAges 11–18 - NCT07471685Recruiting
Family building support for young female cancer survivors
This study tests a decision-support program for female adolescent and young adult cancer survivors who want to plan for having children. It helps you think through your options after cancer treatment.
Durham, North CarolinaAges 18–39 - NCT07573085Recruiting
Online emotion regulation therapy for adolescents who self-injure
This trial tests an online therapy program designed to help teenagers aged 13–17 who have hurt themselves learn better ways to manage difficult emotions. A parent or caregiver will also participate in the program to provide support.
StockholmAges 13–17 - NCT07212166Recruiting
Questionnaires for teens and young adults with cancer
This study asks teens and young adults with cancer to fill out questionnaires about their experience. The answers may help improve care and support for people their age.
Basking Ridge, New JerseyAges 15–39 - NCT07247968RecruitingEarly Phase 1
Esketamine with ECT for severe depression in teens
This study tests whether adding a low dose of esketamine (a type of anesthesia) to modified electroconvulsive therapy (ECT) helps treat severe depression in teenagers. It aims to see if this combination works better and is safer than ECT alone.
ChongqingAges 13–17 - NCT07092917Recruiting
Spinal fusion surgery for teen scoliosis
This trial studies the outcomes and complications of posterior spinal fusion surgery in teens with adolescent idiopathic scoliosis. It aims to help those with moderate to severe curves that are getting worse quickly or causing functional problems.
Asyut, EgyptAges 8–21 - NCT07059078Recruiting
Talk therapy with or without mindfulness for teen drinking
This study tests whether a brief talk therapy session, sometimes combined with mindfulness exercises, can help teens reduce alcohol use. It is designed for teens who get care at Johns Hopkins and already drink alcohol at least once a month.
Baltimore, MarylandAges 12–17 - NCT07693426RecruitingPhase 1
Study of efsubaglutide alfa for obese teenagers
This trial tests an injection called efsubaglutide alfa to help obese teenagers lose weight. It requires following diet and exercise advice for at least 3 months before starting.
Beijing, Beijing MunicipalityAges 12–17 - NCT06081348RecruitingPhase 2
Sertraline vs. placebo for anxiety in kids with developmental disorders
This trial compares sertraline (a common antidepressant) to a placebo (a pill with no medicine) to see which better reduces anxiety in children and teens who also have a neurodevelopmental disorder like autism, ADHD, or Tourette's. The goal is to help you and your child understand if this treatment might offer relief from anxiety.
Calgary, AlbertaAges 8–17 - NCT06950983Recruiting
Navigating Financial Needs for Young Cancer Survivors
This study is testing a program that helps young people with cancer (ages 15–39) manage money and other everyday needs. It aims to reduce stress and improve well-being during and after treatment.
New York, New YorkAges 15 years+ - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT06575738RecruitingPhase 1
Semaglutide for teens after weight-loss surgery
This study looks at how teenagers and young adults respond to weight-loss surgery (sleeve gastrectomy) and whether adding a medication called semaglutide can help improve weight loss. It has two parts: first observing how surgery affects you, then testing if semaglutide helps those who didn't lose enough weight after surgery.
Aurora, ColoradoAges 12–24 - NCT03582917RecruitingPhase 2
Vitamin D during rehabilitation for teen scoliosis
This study looks at whether vitamin D affects recovery during rehab for teens with idiopathic scoliosis (a sideways spine curve without a known cause). It may help the rehab process by improving vitamin D–related factors in growing teens.
AsvestochóriAges 10–18 - NCT03915106Recruiting
Quality of life in teens with scoliosis needing brace or surgery
This study looks at how much day-to-day quality of life changes for people with adolescent idiopathic scoliosis who either need a brace or need surgery. It uses a short questionnaire to understand how treatment affects comfort, activity, and overall well-being.
ShatinAges Any age - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT04355572Recruiting
Vitamin D replacement study for teens at risk of PCOS
This study looks at how taking vitamin D affects hormone levels and emotional well-being in teen girls who may develop PCOS. If you have low vitamin D and meet PCOS risk criteria, the study may test whether vitamin D helps you feel and function better.
New Haven, ConnecticutAges 13–21 - NCT04441411Recruiting
Non-fusion surgery for teens with idiopathic scoliosis
This trial studies a “non-fusion” surgery approach for teenagers with a spinal curve that has worsened despite non-surgical treatments. It aims to see if this surgery can better treat adolescent idiopathic scoliosis while avoiding spinal fusion in eligible patients.
Amsterdam, North HollandAges 10–17
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Common questions
- Are there clinical trials for adolescence?
- Yes. Clin2 currently lists 952 recruiting adolescence studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a adolescence trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a adolescence trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.