Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,068 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06934057RecruitingPhase 4
Cabozantinib and Nivolumab for older adults with kidney cancer
This trial is testing a combination of two drugs, cabozantinib and nivolumab, in people aged 70 or older who have advanced kidney cancer that hasn't been treated yet. The goal is to see if this combination works well and is safe for older patients.
AngersAges 70 years+ - NCT06919094Recruiting
Virtual club to reduce loneliness in older adults
This trial tests whether a virtual life story club can help older adults feel less lonely and more engaged. You would meet with others online to share memories and stories.
The Bronx, New YorkAges 60 years+ - NCT06922071Recruiting
Memory support program for older adults in care
This study offers a memory- and thinking-support program for older adults who are living in a residential facility or attending a daycare center. The goal is to help keep your mind sharp and maintain your well-being as you age.
Coimbra, PortugalAges 65 years+ - NCT06916221Recruiting
Digital brain training in aging
This study tests whether a digital intervention can help older adults (60+) maintain or improve cognitive function. It is designed for healthy adults or those with mild cognitive impairment (MCI), and people who do not regularly play a musical instrument or have extensive music training.
San Francisco, CaliforniaAges 60–85 - NCT06894927Enrolling by invitation
Hearing check for adults 50 and over
This trial offers a free hearing check for adults aged 50 and older. It aims to detect any hearing changes early and can help you understand your hearing health better.
Hradec Králové, Czech RepublicAges 50 years+ - NCT06894914Recruiting
Physical activity counseling for older adults with complex health needs
This study looks at ways to help older adults with multiple health conditions get more physical activity. It compares two types of counseling that physiotherapists provide. You may be eligible to take part if you are 65 or older, live in the community, have certain health challenges, and can walk a short distance.
Vancouver, British ColumbiaAges Up to 99 years - NCT06893419Recruiting
Telehealth for nursing home residents after hospital stay
This trial tests a telehealth program to help nursing home residents manage their health after a recent hospital stay. It may improve your recovery and keep you healthier.
AnconaAges 70 years+ - NCT06896825Recruiting
Staying active with social support and stress relief
This study tests whether a program that combines social support and stress management can help older adults who live alone become more physically active. You'll use a smartphone to track your activity and get support from others.
Phoenix, ArizonaAges 60 years+ - NCT05492708Recruiting
Pregnancy study for first-time-to-mid pregnancy participants in Heartland states
This study is enrolling pregnant people who are early in pregnancy and live in certain Heartland states. It aims to learn from participants during pregnancy and may help researchers better understand pregnancy care needs.
Indianapolis, IndianaAges 18 years+ - NCT06889545Recruiting
Comparing ways to measure frailty before surgery in older adults
This trial compares different ways to measure frailty in people aged 70+ before surgery lasting at least 2 hours, to see which tool works best.
HamburgAges 70 years+ - NCT06882889Recruiting
Comparing domestic vs imported hearing aids for age-related hearing loss
This trial compares two types of hearing aids (one made in China, one imported) to see which works better for age-related hearing loss. You might benefit if you have moderate to severe hearing loss and are willing to test both devices.
Guangzhou, GuangdongAges 60–85 - NCT06890403Recruiting
Can stories help older adults get vaccinated?
This trial tests whether watching personalized story videos along with informational videos can encourage older adults to get recommended vaccines. It aims to see if these videos are more effective than standard information alone.
New York, New YorkAges 50 years+ - NCT06864715Recruiting
Preventing depression after a stroke with behavioral activation
This study tests if a talking therapy called behavioral activation can prevent depression in older adults who have had a stroke and have low income. It is for people who are not already severely depressed and live at home.
Houston, TexasAges 55 years+ - NCT05582772Recruiting
Supportive care for older men with metastatic prostate cancer
This study tests a phone-based supportive care program for older men with prostate cancer. It aims to help with day-to-day management while you’re receiving hormone-related cancer treatment.
Toronto, OntarioAges 65 years+ - NCT06854731Recruiting
Preventing falls in older adults with cognitive frailty
This trial studies a program to help older adults with mild memory problems and physical frailty reduce their risk of falling. It tests a home-based exercise and fall-prevention plan to improve strength and balance.
Vancouver, British ColumbiaAges 65–89 - NCT06842173RecruitingPhase 1/Phase 2
Safety testing of new bird flu vaccine (H5N8) in adults
This trial tests a new bird flu (H5N8) vaccine for adults aged 18 and older. It looks at how safe the vaccine is and how well it triggers an immune response. The vaccine is given as a shot and includes an adjuvant to boost protection.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06836440Recruiting
Do glasses help thinking in rural older adults?
This study tests whether giving glasses to older adults in rural areas can improve their thinking and memory. If you have vision problems that can be corrected with glasses, you may be able to join and help us find out if better sight helps your brain stay sharp.
Ya'an, SichuanAges 60–79 - NCT06837857RecruitingPhase 2
Opioid pain relief study for older adults with chronic pain
This study tests whether a carefully managed prescription opioid can safely help older adults with long-term pain that hasn't been relieved by other pain medicines. The goal is to see if it improves pain without harming memory or brain health.
Rochester, MinnesotaAges 65 years+ - NCT06828991RecruitingPhase 2
Mosunetuzumab for older DLBCL patients with residual ctDNA
This trial tests whether adding a targeted immunotherapy drug called mosunetuzumab after standard chemotherapy can help older adults with DLBCL who still have tiny traces of cancer DNA in their blood. If you qualify, the goal is to reduce the chance of the cancer coming back.
Rochester, New YorkAges 70 years+ - NCT06835530RecruitingPhase 2
Rituximab and CC-99282 for older frail patients with large b-cell lymphoma
This trial tests a combination of two drugs, rituximab and CC-99282, as a first treatment for older adults with diffuse large b-cell lymphoma who are too frail for standard chemotherapy. The goal is to see if this gentler approach can effectively control the disease while being easier to tolerate.
Alessandria, AlessandriaAges 80 years+ - NCT06831019Recruiting
The ROAR Study: Oxygen and Reproduction
This study looks at how oxygen levels might affect egg health and embryo development in people undergoing IVF with genetic testing (PGT-A). The goal is to see if changing oxygen during the IVF process can improve the chance of having a healthy baby.
San Francisco, CaliforniaAges 18–43 - NCT06821100RecruitingPhase 1
Thymalfasin to Boost COVID-19 Vaccine Response in Older Adults
This trial tests whether a drug called thymalfasin (thymosin alpha 1) can help older adults (65+) get a stronger immune response from their COVID-19 booster shot. It may be especially helpful for those whose immune systems have weakened with age.
Houston, TexasAges 65–100 - NCT06819254RecruitingPhase 4
Fisetin for fatigue in older cancer survivors
This study tests whether a natural compound called fisetin can reduce fatigue in people aged 60+ who have completed cancer treatment. If you still feel tired often, this pill-based treatment might help you regain energy.
Winston-Salem, North CarolinaAges 65 years+ - NCT06809868Recruiting
Study of genetic elements in sepsis and aging
This trial looks at how certain genetic elements may affect the immune system in older adults with sepsis. It aims to understand why older patients may respond differently to severe infections.
San Francisco, CaliforniaAges 18 years+
Hear when a new Aged 65 Years or Older trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,068 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.