Clinical trials
Aged 65 Years or Older clinical trials
Below are recruiting aged 65 years or older clinical trials, each written for real people, not researchers. We’re tracking 1,067 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07252583Recruiting
Sexuality and mental health in older adults
This study looks at how sexuality and mental health are connected in older adults. It involves a questionnaire about your experiences and feelings, with no treatments or medications.
Clermont-FerrandAges 60 years+ - NCT07064551Recruiting
Combining medical and community support for depression
This study tests a new way of combining medical care with community support for middle-aged and older adults who have depression and are waiting for mental health services. The goal is to see if this team approach can help improve mood and well-being while you wait.
Hong KongAges 45 years+ - NCT07023146Enrolling by invitation
Power training for older adults: comparing different intensities
This study compares different power training intensities for older adults to see which is most effective. If you are 60 or older and not currently doing strength training, you may be eligible.
Porto Alegre, Rio Grande do SulAges 60 years+ - NCT06948136RecruitingPhase 1
THC effects in older adults trial
This trial studies how a single dose of THC (the active ingredient in cannabis) affects older adults. It aims to understand the effects in this age group, which may help guide safe use.
West Haven, ConnecticutAges 21 years+ - NCT07742397Recruiting
Leg strength and balance in adults over 65
This study looks at how differences in strength and function between your left and right legs might affect your risk of falling. If you join, you'll help researchers understand why some older adults fall and others don't, which could lead to better fall prevention.
Milan, MilanAges 65 years+ - NCT06633978Recruiting
Digital tools for brain health in older adults
This study tests if using digital tools (like apps or computer programs) can improve memory, thinking, mood, stress, and sleep in healthy older adults. You will use the tools at home or in the lab, and researchers will track changes.
San Francisco, CaliforniaAges 60–85 - NCT06596304Recruiting
How blood vessels respond to exercise with and without blood flow restriction
This study looks at how your blood vessels respond to resistance exercise (like weight lifting) with and without a technique called blood flow restriction. It compares younger and older adults to understand how aging affects these responses.
Almada, Monte Da CaparicaAges 18 years+ - NCT06622889Enrolling by invitation
Can changing how you see aging help memory?
This study tests whether changing how older adults think about aging can help with memory concerns. If you are 60+ and feel your memory or thinking is declining (but tests are normal), you may be able to join.
Beijing, Beijing MunicipalityAges 60 years+ - NCT07727551Recruiting
Nerve block before knee replacement for better recovery
This trial tests if a nerve block given a few weeks before knee replacement surgery can improve pain and function after the operation. It is designed for people who have certain risk factors that might make recovery harder.
BrusselsAges 18–60 - NCT06567665Recruiting
Leucine supplement for muscle building in older men
This study tests if taking a leucine supplement (an amino acid found in protein) can help older men build muscle more effectively. You may be eligible if you are a healthy, non-smoking man between 65 and 75 who does not currently do weight training.
Nottingham, NottinghamshireAges 65–75 - NCT07209683Recruiting
Near-infrared light therapy for brain function in adults
This study tests whether shining a special near-infrared light on the head can improve how well your brain works and how clearly you think. It is for healthy younger and older adults who want to help find new ways to support brain health.
Oklahoma City, OklahomaAges 21–85 - NCT07388043Recruiting
AP-Brain for memory in older adults with memory concerns
This trial tests a supplement called AP-Brain to see if it helps with memory and thinking in healthy middle-aged and older adults who notice memory problems. You would take different doses of the supplement or a placebo for several weeks and complete memory tests.
London, OntarioAges 40–79 - NCT06137339Recruiting
Daily avocado and cognition in older adults
This study tests whether eating one avocado daily for 6 months can help keep your thinking and memory sharp as you age. You must not currently eat many avocados or vegetables, and be willing to change your diet.
Kansas City, KansasAges 65–85 - NCT06649500Recruiting
Comparing two balance therapy methods for older adults
This trial tests whether a high-tech treadmill (Walker View) or group therapy works better for improving balance and preventing falls in older adults. It also uses artificial intelligence to predict fall risk early.
Rome, RomeAges 65 years+ - NCT07621523Recruiting
How Pilates Affects Energy Use in Older Adults
This study measures how much energy your body uses during Pilates exercises and how it affects your metabolism. Researchers want to understand if regular Pilates is a good way for older adults to stay active and healthy.
Jacarezinho, ParanáAges 60 years+ - NCT07112573Recruiting
Medications for mental health and falls risk in older adults
This study looks at whether certain medications for mental health (called psychotropic drugs) are linked to a higher risk of falls in adults 60 and older.
Cairo, AbbassiaAges 60 years+ - NCT07045259Recruiting
Exergaming vs. exercise for memory and movement in seniors
This study compares fun video games that get you moving (exergaming) with standard muscle-strengthening exercises. It aims to see which one better helps older adults who have both slower walking speed and memory concerns.
BalıkesirAges 65 years+ - NCT06029933Recruiting
Comparing two flu vaccines for older adults
This study compares two types of flu shots for people 65 and older to see which works better. If you are a Kaiser Permanente member and get your flu shot at a Kaiser facility, this trial looks at your health records to see how well the vaccine protected you.
Oakland, CaliforniaAges 65 years+ - NCT07740694Recruiting
ECT study for older adults with depression
This study looks at how ECT affects brain activity and inflammation in older adults with depression. It may help researchers understand why ECT works and improve treatment.
Istanbul, BakırköyAges 55 years+ - NCT07345832Recruiting
Volunteer-led lifestyle program for older adults with muscle loss
This study tests a volunteer-led program to improve muscle health in older adults with sarcopenia. It uses a mobile app to guide exercise and nutrition, and aims to see if this approach helps people regain strength.
Hong KongAges 60 years+ - NCT07732530Recruiting
Acupoint Stimulation and Exercise for Pre-Frail Older Adults
This study tests whether combining acupoint stimulation (a type of pressure on specific body points) with exercise can help older adults who are starting to become frail. It aims to improve strength and daily function.
TainanAges 50 years+ - NCT07285005RecruitingPhase 3
Study of an oral drug for venous, lymphatic, and certain overgrowth syndromes
This trial tests whether the study drug KP-001 can help reduce symptoms like pain, fatigue, or bleeding caused by certain vascular malformations (abnormal blood vessel growths) that can't be surgically removed or haven't responded to other treatments. It's for people age 2 and older with specific conditions such as common venous malformations, lymphatic malformations, or KTS/CLOVES syndrome.
Charleston, South CarolinaAges 2 years+ - NCT03451383Recruiting
Study brain changes in older breast cancer patients
This study follows older women with newly diagnosed breast cancer to see who might develop thinking or memory problems over time. It may help researchers understand early brain risk and how treatment and other factors relate to cognitive decline.
Washington D.C., District of ColumbiaAges 60–105 - NCT03761446Recruiting
Testing how diabetes affects muscle loss after bed rest
This study looks at how pre-diabetes or type 2 diabetes may change skeletal muscle loss and recovery in older adults after a period of bed rest. It may help researchers understand why recovery can be slower and how to better protect muscle in people as they age.
Orlando, FloridaAges 60–80
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Common questions
- Are there clinical trials for aged 65 years or older?
- Yes. Clin2 currently lists 1,067 recruiting aged 65 years or older studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a aged 65 years or older trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a aged 65 years or older trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.