Clinical trials
Alzheimer s Disease clinical trials
Below are recruiting alzheimer s disease clinical trials, each written for real people, not researchers. We’re tracking 593 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04124029Recruiting
Study how mild brain injuries may relate to dementia
This study looks at how past mild traumatic brain injury may contribute to brain changes seen in chronic traumatic encephalopathy (CTE) and Alzheimer’s disease (AD). It may help researchers understand risk and brain markers by comparing people with mild or moderate TBI, people with mild memory problems, and healthy controls.
Boston, MassachusettsAges 30–90 - NCT05016219Recruiting
Light therapy to improve sleep and thinking in early Alzheimer’s
This trial studies rhythmic light therapy to help people with early Alzheimer’s or mild memory problems, especially when sleep is getting worse. If you fit the sleep and vision/medical safety requirements, the study may see whether the therapy improves sleep and thinking-related symptoms.
Menands, New YorkAges 55 years+ - NCT05260177Recruiting
40 Hz light therapy for mild to moderate Alzheimer’s
This study tests whether a non-invasive 40 Hz light therapy system can help people with early Alzheimer’s. You’ll likely use the device at home and wear a small activity monitor, while doing memory and thinking tests.
RoskildeAges 40 years+ - NCT05282550RecruitingPhase 2
Trazodone trial to improve sleep in early Alzheimer’s
This study tests whether the sleep medicine trazodone can improve thinking and memory in people with early Alzheimer’s-related changes who also have sleep problems. If better sleep helps the brain, it may improve memory test results over time.
Baltimore, MarylandAges 55 years+ - NCT05452031Recruiting
Sleep program for people with dementia and their caregiver
This study tests a “dyadic” sleep health approach, meaning it works with both you and your caregiver together. It aims to improve sleep when dementia is causing frequent sleep problems, and to see whether a caregiver-involved plan helps both of you.
La Jolla, CaliforniaAges 18 years+ - NCT05558709Recruiting
Test for thinking and behavior skills in neurodegenerative disease
This trial checks a new kind of paper-and-pen (or computer-based) test to better measure thinking and social/behavior skills in people with certain brain diseases. It may help researchers improve how these skills are tracked and understood over time.
ParisAges 18–90 - NCT05591027RecruitingPhase 1
Testing Centella asiatica for memory problems in older adults
This Phase 1 study tests whether Centella asiatica (a plant-based supplement) is safe and reaches its intended target in people with mild cognitive impairment or early Alzheimer’s disease. It also checks how it affects memory-related brain measures like MRI scans, which is why multiple scans are required.
Portland, OregonAges 60–85 - NCT05592678Recruiting
Study brain and memory test changes in Alzheimer’s or mild issues
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
San Antonio, TexasAges 65–100 - NCT05623124Recruiting
Alzheimer’s and dementia brain and memory study with caregiver support
This is a study that enrolls people with mild Alzheimer’s-related memory problems or dementia to help build a research “neurobank.” It also involves memory testing and may include brain scans, with a stable caregiver to support follow-up.
Shanghai, Shanghai MunicipalityAges 50–90 - NCT05629871Recruiting
Tracking sleep changes in early Alzheimer’s and thinking decline
This study looks at how sleep and wake patterns change in people with early Alzheimer’s, and whether these changes relate to memory and thinking decline. You may be asked to do questionnaires, sleep diaries, and possibly a diagnostic spinal fluid test (lumbar puncture) to measure biomarkers.
MontpellierAges 50–85 - NCT05649514Recruiting
Studying sleep problems in early Alzheimer’s risk patients
This study looks at sleep problems in people with mild Alzheimer’s disease and whether sleep measurements and questionnaires can help researchers understand early changes. You may be able to join if your diagnosis is mild and you can complete repeated sleep and thinking questionnaires with a family caregiver’s help.
Montpellier, HéraultAges 50–85 - NCT05658913Recruiting
Tau PET/CT scan study for people in an ongoing cohort
This study uses a special brain scan (tau PET/CT) to look for a protein called tau, and it ties the scan results to information collected in an existing research program. It may help researchers better understand brain changes over time.
Boston, MassachusettsAges 18–120 - NCT05822362RecruitingPhase 2
CBD for People with Early Memory Trouble Risk
This Phase 2 study tests whether CBD (a cannabis-derived product) can improve thinking and memory in people who are at risk for Alzheimer’s disease. You would be followed for about 24 weeks with memory/thinking check-ins and require a study partner to help with certain assessments.
Aurora, ColoradoAges 55–85 - NCT05877391Recruiting
Collecting sexual and gender identity information in hospice
This study tests an approach to collect and use sexual orientation and gender identity (often called “SOGI”) information for people receiving hospice care. The goal is to help hospice teams better understand and support patients’ needs.
Aurora, ColoradoAges 18 years+ - NCT05887674Recruiting
Non-drug memory program for early Alzheimer’s and memory loss
This trial studies a non-medication (non-drug) program to improve memory and daily thinking in people with mild cognitive impairment or mild Alzheimer’s disease. It may help by supporting brain function and monitoring symptoms over time.
Shanghai, Shanghai MunicipalityAges 60–90 - NCT05943834Recruiting
Voice testing to detect early memory and mood changes
This trial studies whether automated analysis of your voice and speech can help detect early signs of Alzheimer’s disease and mood (affective) problems. It may help identify changes sooner, using voice and questionnaire information from people who are cognitively healthy to very mildly affected.
NiceAges 50–100 - NCT06089161Recruiting
Sleep Apnea Treatment and Alzheimer's Risk in Black Adults
This trial tests whether personalized sleep apnea treatment can help protect memory and thinking in Black older adults. If you have sleep apnea and are concerned about Alzheimer's, this study may help you and others like you.
Miami, FloridaAges 60–85 - NCT06152211Recruiting
Music therapy for aging and Alzheimer's disease
This trial tests if music-based activities can help older adults with or without Alzheimer's. You'll attend weekly music sessions and be assessed over time.
Los Angeles, CaliforniaAges 65 years+ - NCT06183658Recruiting
Healthy Brain Aging Study for Adults 55–90
This study looks at healthy brain aging in older adults. It involves brain scans, blood tests, and regular check-ins to understand how memory and thinking change over time.
Shenzhen, OtherAges 55–90 - NCT06215274Recruiting
Leisure activities and early Alzheimer's study
This trial looks at how engaging in mentally stimulating leisure activities (like puzzles, reading, or games) may affect brain health in people with early memory concerns. Researchers want to understand the brain changes that happen with these activities.
Fuzhou, FujianAges 60 years+ - NCT06313853Recruiting
Communication support for older adults with dementia and cancer
This study tests a communication coaching session to help older adults with both dementia and cancer talk with their family and doctors about treatment decisions. The goal is to make sure your wishes and needs are heard.
Rochester, New YorkAges 65 years+ - NCT06649929Enrolling by invitationPhase 2
Better sleep for Latino couples and brain health
This study tests a program to help Latino couples improve sleep and CPAP use, which may lower Alzheimer's risk. You and your partner will join telehealth sessions together.
Tuscon, ArizonaAges 35 years+ - NCT06337578Recruiting
Telephone-based cognitive screening study
This study tests if a phone-based cognitive screening can effectively assess thinking and memory. It may help people who can't easily visit a clinic.
MilanAges 18–100 - NCT06411561Recruiting
Boosting memory after ICU stay for older adults
This study tests a combination of activities (like cognitive training and exercise) to help older adults recover thinking and memory after a serious illness in the ICU. It may help you regain sharpness and independence after leaving the intensive care unit.
Seattle, WashingtonAges 60 years+
Hear when a new Alzheimer s Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for alzheimer s disease?
- Yes. Clin2 currently lists 593 recruiting alzheimer s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a alzheimer s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a alzheimer s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.