Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 540 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04580225Recruiting
Tested partial wrist fusion with or without bone removal
This study compares two surgical options for certain types of advanced wrist arthritis—one with partial wrist fusion alone, and one with partial wrist fusion plus removal of a small wrist bone. It may help find which approach works better for pain and function after surgery.
Calgary, AlbertaAges 18–75 - NCT03755245Enrolling by invitation
Imaging study using a tracer to measure inflammation in joints and lungs
This trial tests how a radioactive imaging medicine (a tracer called 68Ga-DOTA-Siglec-9) spreads in the body and how well it shows inflammation. It includes both healthy volunteers and people with active rheumatoid arthritis, vasculitis, or pulmonary sarcoidosis to see if the scan matches disease activity.
TurkuAges 18–70 - NCT03816345RecruitingPhase 1
Nivolumab for advanced cancer with autoimmune disease
This trial tests whether the immunotherapy drug nivolumab can safely treat advanced cancer in people who also have an autoimmune disease like rheumatoid arthritis, lupus, or multiple sclerosis. It aims to find out if the drug may help control cancer while managing their autoimmune condition.
Birmingham, AlabamaAges 18 years+ - NCT03773965RecruitingPhase 3
Baricitinib study for kids with juvenile arthritis
This study tests baricitinib, a medicine, in children and teens with juvenile idiopathic arthritis. It includes only families who already took baricitinib in an earlier study and did not stop it permanently or develop an allergy.
RosarioAges 1–18 - NCT03722537Recruiting
Test of cartilage graft surgery for thumb arthritis pain
This trial looks at using a donated cartilage-and-bone graft during surgery for thumb “basal joint” arthritis. It may help reduce pain and improve thumb function if you are planning surgery for this condition.
New York, New YorkAges 18 years+ - NCT00748254Recruiting
Laser imaging test for rheumatoid arthritis inflammation
This study uses a laser-based imaging method to “see” inflammation in people with rheumatoid arthritis. It may help researchers better understand how active joint inflammation looks and how it changes.
Ann Arbor, MichiganAges 18 years+ - NCT03704766Recruiting
Testing fluid markers to detect pediatric joint infections
This study checks special lab markers in joint fluid to tell septic (infected) arthritis apart from other inflammatory causes in children. It may help clinicians detect infection more accurately and quickly so kids can get the right treatment.
Atlanta, GeorgiaAges Up to 17 years - NCT03429426Enrolling by invitation
Tracking joint bone damage in rheumatoid arthritis with scans
This study uses high-resolution scans and regular X-rays to see how bone erosions (bone wear) progress in people with rheumatoid arthritis over time. It may help researchers better understand disease changes and how to measure them.
AarhusAges 18 years+ - NCT03414502RecruitingPhase 3
Predictors of Response to DMARDs in Rheumatoid Arthritis
This trial studies rheumatoid arthritis (RA) patients starting or adjusting DMARD medicines and looks for signs that predict who responds best. It may help doctors choose more effective treatment sooner.
Omaha, NebraskaAges 19 years+ - NCT03297775Recruiting
Studying rheumatoid arthritis treatment risks for lung scarring
This trial is for people with rheumatoid arthritis (RA) who are at risk for developing interstitial lung disease, which is scarring in the lungs. It aims to better understand why this happens and how to help prevent or manage it.
Aurora, ColoradoAges 45–90 - NCT03192267Recruiting
Study of lung changes in early rheumatoid arthritis
This study looks at lung health in people with early rheumatoid arthritis (RA). It may help doctors understand how RA affects the lungs soon after diagnosis and guide better care.
Omaha, NebraskaAges 19–90 - NCT02991469RecruitingPhase 2
Testing sarilumab for children with systemic juvenile arthritis
This trial studies sarilumab, a targeted medicine, to help reduce symptoms in children and teens with systemic juvenile idiopathic arthritis (sJIA) who have not responded enough to current treatments. You may be considered because the study looks at how well and safely repeated doses work in pediatric patients.
San Miguel de Tucumán, Tucumán ProvinceAges 1–17 - NCT02530268Enrolling by invitation
Registry for psoriatic arthritis and spine arthritis patients starting treatment
This is a patient registry that tracks people with psoriatic arthritis or spine inflammatory arthritis when they start a specific new treatment. It helps researchers learn about real-world outcomes and safety as patients receive care over time.
Ages 18 years+ - NCT01402661Enrolling by invitation
Rheumatoid arthritis drug safety and effectiveness registry
This registry collects real-world information about people with rheumatoid arthritis (RA) to help doctors understand how RA medicines work and their safety. You may be able to join if you’re newly diagnosed or starting certain RA treatments and you’re willing to share consent and basic personal details.
Waltham, MassachusettsAges 18 years+ - NCT01422694Recruiting
Understanding spondyloarthritis over time
This study follows people with spondyloarthritis (an inflammatory arthritis that often affects the spine and joints) and their family members over time to better understand how the disease develops and progresses. It also includes a research stool sample test to learn about gut bacteria.
Bethesda, MarylandAges 2–99 - NCT00024479Recruiting
Understanding how rheumatic diseases develop over time
This research study follows people with known or suspected rheumatic diseases (like arthritis, lupus, or similar conditions) to learn how these conditions change and progress naturally. By tracking your health over time, researchers hope to better understand these diseases and improve treatments.
Bethesda, MarylandAges 18–100 - NCT07602595Recruiting
Early-life health risks and chronic pain in teens and young adults
This study looks at how early health problems might affect pain that lasts a long time. If you had a muscle or joint surgery, or a rheumatic disease, before age 18, you might help us understand why some people get ongoing pain.
Cincinnati, OhioAges 14–26 - NCT05147675RecruitingPhase 1
Testing cord stem cell treatment for osteoarthritis safety
This early study (Phase 1) checks whether an infused stem cell product made from donated umbilical cord tissue is safe in people with osteoarthritis. It’s mainly looking for side effects and whether the treatment can be given safely.
Naples, FloridaAges Any age - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80 - NCT06712628Recruiting
Comparing how long people stay on upadacitinib vs TNF inhibitors for RA
This study compares how well people with rheumatoid arthritis stay on two types of medicines: upadacitinib (Rinvoq) and TNF inhibitors. It looks at real-world experiences in Germany to see if one medicine is more likely to be continued over time.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT03650010Recruiting
Study of ankle replacement outcomes over many years
This study looks at how well total ankle replacement surgery works and what the scans show over time. It mainly includes adults who had the surgery in a specific date range, to better understand results after ankle replacement.
Milan, MilanoAges 18 years+ - NCT03770702RecruitingPhase 3
Testing blood pressure pills and statins for rheumatoid arthritis
This trial studies whether taking a cholesterol-lowering medicine (a statin) and a blood pressure medicine (an ARB) can better control rheumatoid arthritis activity. It may help people whose rheumatoid symptoms are not fully controlled with standard care.
TantaAges 18–65 - NCT03770923RecruitingPhase 3
Testing medicines for rheumatoid arthritis activity
This trial studies whether certain medicines can improve how active rheumatoid arthritis is. If you have rheumatoid arthritis and do not have significant liver or kidney problems, you may be able to join.
TantaAges 18 years+ - NCT03473912Recruiting
Rheumatoid disease biobank study for adults
This study asks adults with a rheumatoid condition to join a biobank, which is a safe place to store health information and biological samples for future research. It may help researchers better understand rheumatoid conditions and develop better treatments.
Kfar SabaAges 18–120
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 540 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.