Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 558 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06469177Enrolling by invitation
Pain management app study for joint replacement recovery
This study tests a smartphone tool to help manage pain after hip, knee, or shoulder replacement. It aims to see if using the tool improves your recovery compared to standard care.
Dartmouth, Nova ScotiaAges 19 years+ - NCT05799768Enrolling by invitation
Ketogenic diet for rheumatoid arthritis symptoms and inflammation
This study tests whether a very low-carbohydrate, ketogenic diet can improve rheumatoid arthritis (RA). It’s designed for people whose RA treatment is already stable and who are not currently using a keto diet or certain medicines.
Oklahoma City, OklahomaAges 18–65 - NCT05500066Enrolling by invitation
Shoulder implant study for people needing shoulder replacement
This trial studies a specific shoulder replacement implant system. It may help people with damaged shoulder joints by testing how well the implant works and how it affects recovery and function.
Denver, ColoradoAges 18 years+ - NCT03755245Enrolling by invitation
Imaging study using a tracer to measure inflammation in joints and lungs
This trial tests how a radioactive imaging medicine (a tracer called 68Ga-DOTA-Siglec-9) spreads in the body and how well it shows inflammation. It includes both healthy volunteers and people with active rheumatoid arthritis, vasculitis, or pulmonary sarcoidosis to see if the scan matches disease activity.
TurkuAges 18–70 - NCT03429426Enrolling by invitation
Tracking joint bone damage in rheumatoid arthritis with scans
This study uses high-resolution scans and regular X-rays to see how bone erosions (bone wear) progress in people with rheumatoid arthritis over time. It may help researchers better understand disease changes and how to measure them.
AarhusAges 18 years+ - NCT05440422RecruitingPhase 2
Anifrolumab for heart and blood vessel health in lupus
This trial tests whether a drug called anifrolumab can improve early signs of heart and blood vessel damage in people with lupus. It may help prevent future heart problems and strokes.
Bethesda, MarylandAges 18–80 - NCT07774507Recruiting
Daily movement and artery health in rheumatoid arthritis
This study looks at how daily movement patterns (like sitting, standing, and walking) relate to the buildup of plaque in arteries (atherosclerosis) in people with rheumatoid arthritis. It aims to understand if certain activity levels can lower heart risks.
Presidente Prudente, São PauloAges 18–65 - NCT07310849Recruiting
Digital health support for older adults with diabetes
This study tests a digital care program using the LINE messaging app to help older adults with diabetes and other chronic conditions manage their health. It may be a good fit if you are 50 or older, have type 2 diabetes plus another condition like high blood pressure, and are comfortable using a smartphone.
New Taipei City, Wugu DistrictAges 50 years+ - NCT06058169Recruiting
Home vibration therapy for arthritis knee pain
This study tests if doing whole-body vibration exercises at home can help reduce knee pain from arthritis. You stand on a gently vibrating platform for short periods over several weeks.
Augusta, GeorgiaAges 40–75 - NCT07778069Enrolling by invitation
Virtual reality for children having joint steroid injections
This study tests whether using virtual reality (VR) during a steroid joint injection helps children feel less pain and anxiety. If it works, it could make the procedure easier for patients from 5 to 17 years old.
Columbus, OhioAges 5–17 - NCT07639060Recruiting
Pain Relief Study Using Freezing Nerve Treatment
This study watches how well a freezing procedure works for chronic pain over 6 to 12 months. Your doctor thinks this procedure could help your pain, and the study simply tracks your recovery through questionnaires to help doctors understand if it works.
Old Saybrook, ConnecticutAges 18 years+ - NCT02471352Recruiting
Share skin samples for dermatology research
This study collects and stores biological samples (biospecimens) from people with skin conditions, people at risk, or healthy volunteers. It helps researchers better understand dermatologic diseases and support future skin research.
Bethesda, MarylandAges 1 day–100 years - NCT07473154RecruitingPhase 1/Phase 2
Calming an overactive immune system with special cells
This trial tests a new type of cell therapy made from a patient's own white blood cells (called lymphocytes) that are designed to help control the immune system. The goal is to reduce inflammation and symptoms in people with hard-to-treat rheumatoid arthritis or a severe form of scleroderma (dcSSc).
DüsseldorfAges 18 years+ - NCT06570798RecruitingPhase 2
Testing Two Drugs for Lupus and Rheumatoid Arthritis
This trial tests two study drugs, inebilizumab and blinatumomab, for people with lupus (SLE) or rheumatoid arthritis (RA) that hasn't gotten better with standard treatments. It focuses on those with active disease, especially lupus-related kidney problems.
Scottsdale, ArizonaAges 18–75 - NCT07383740Recruiting
Reliability of a gentle bike test for hip or knee osteoarthritis
This study checks whether a simple, low-effort bike test gives consistent results for people with hip or knee osteoarthritis. It helps doctors understand how well this test can measure your fitness without pushing you too hard.
GothenburgAges 30 years+ - NCT07473232Recruiting
Comparing platelet-rich plasma and cytokine-rich serum injections for knee osteoarthritis
This trial compares two types of injections (PRP and ACS) to see which one works better for knee osteoarthritis. It may help people with knee pain who have not had these injections recently.
Pamukkale, DenizliAges 40–80 - NCT05277025Recruiting
Brain pain testing in long-term joint pain and fibromyalgia
This study looks at how the brain processes pain in people with long-term pain conditions like fibromyalgia and rheumatoid arthritis. You may be asked to undergo pain-related tasks to help researchers understand differences between inflammatory and non-inflammatory chronic pain.
Gainesville, FloridaAges 18–70 - NCT07767812Recruiting
Motivational interviewing for knee osteoarthritis pain
This study tests whether talking with a counselor (motivational interviewing) helps people with knee osteoarthritis feel more confident in managing their pain and become more physically active. It may help you feel better and move more easily.
Afyonkarahisar, TürkiyeAges 40 years+ - NCT07627893RecruitingPhase 2/Phase 3
Herbal supplement added to rheumatoid arthritis treatment
This trial tests whether a traditional Chinese herbal medicine, combined with your current rheumatoid arthritis medications, can reduce joint pain and swelling better than your current treatment alone. The study involves 6–12 months of treatment and regular check-ins with the research team.
SingaporeAges 21–70 - NCT06451588RecruitingPhase 2
Fecal transplant for inflammatory back pain
This study tests whether a fecal microbiota transplant (a procedure that transfers healthy bacteria into your gut) can reduce inflammation and improve symptoms in people with inflammatory back pain (axial spondyloarthritis). It may help if your current treatments are not working well enough.
TromsøAges 18–65 - NCT07764354Recruiting
Patient education for sticking with home exercises
This study tests whether extra education helps people with chronic musculoskeletal conditions—like long-term back pain, knee arthritis, or partial rotator cuff tears—stick with their home exercise routines to feel better. If you have one of these conditions and are willing to follow a home exercise plan, this could help you manage pain.
Dammam, Eastern ProvinceAges Any age - NCT06162195Recruiting
Comparing a new hip implant to standard hip replacement
This trial compares a new hip implant (H1) to a standard total hip replacement. It is for people who need hip replacement on one side due to arthritis or other hip conditions and can commit to long-term follow-up.
BournemouthAges Any age - NCT06618820Enrolling by invitationPhase 3
Extended tranexamic acid after knee replacement
This trial tests whether taking tranexamic acid (a medicine that helps blood clot) for several days after knee replacement surgery reduces bleeding and improves recovery. It may help patients who have a standard knee replacement and are not on blood thinners.
Germantown, TennesseeAges 18 years+ - NCT07522489Recruiting
New knee replacement surgery guidance methods compared
This study compares two ways doctors use computer guidance during robotic knee replacement surgery for severe knee arthritis. The trial tests whether both methods work equally well or if one is better for patient recovery and results.
Warsaw, MazovianAges 18 years+
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 558 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.