Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 552 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03473912Recruiting
Rheumatoid disease biobank study for adults
This study asks adults with a rheumatoid condition to join a biobank, which is a safe place to store health information and biological samples for future research. It may help researchers better understand rheumatoid conditions and develop better treatments.
Kfar SabaAges 18–120 - NCT03728478RecruitingPhase 3
Step-up and step-down treatment for newly diagnosed arthritis
This Phase 3 study tests whether children with early juvenile idiopathic arthritis do better by starting with one treatment approach and adjusting (stepping up or stepping down) based on how their arthritis responds. It may help find the safest, most effective long-term plan for controlling symptoms with fewer side effects.
Genova, GEAges 2–17 - NCT03770702RecruitingPhase 3
Testing blood pressure pills and statins for rheumatoid arthritis
This trial studies whether taking a cholesterol-lowering medicine (a statin) and a blood pressure medicine (an ARB) can better control rheumatoid arthritis activity. It may help people whose rheumatoid symptoms are not fully controlled with standard care.
TantaAges 18–65 - NCT03770923RecruitingPhase 3
Testing medicines for rheumatoid arthritis activity
This trial studies whether certain medicines can improve how active rheumatoid arthritis is. If you have rheumatoid arthritis and do not have significant liver or kidney problems, you may be able to join.
TantaAges 18 years+ - NCT03913962Recruiting
Exercise study for children with chronic or autoimmune conditions
This study looks at how physical activity affects muscle, metabolism (how your body uses energy), and body composition in children with certain chronic or autoimmune conditions. It may help doctors understand what types of exercise and monitoring are most beneficial and safe.
Clermont-FerrandAges 6–18 - NCT03938701RecruitingPhase 2
Imaging gut and joint inflammation with adalimumab and a light tracer
This study uses a special “light tracer” medicine with adalimumab to see where inflammation is in the gut (IBD) or joints (RA). If you have active disease, it may help doctors better target treatment by showing inflammation more clearly during scans.
Groningen, Provincie GroningenAges 18 years+ - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT04028687Recruiting
Study of a hip stem used in select adult hip replacements
This trial follows people who have had a hip replacement using a specific “Taperloc Complete” stem. It is meant to monitor outcomes after surgery and see how well the stem performs over time for certain non-infectious hip problems.
Henderson, NevadaAges 18 years+ - NCT04209504Recruiting
Nerve block study for one-sided breathing muscle weakness after shoulder surgery
This trial tests whether a longer-lasting nerve block during shoulder surgery can better manage pain and affect one-sided diaphragm (breathing muscle) weakness. It may help people having planned (first-time) shoulder surgery who are able to follow study pain-checks.
Durham, North CarolinaAges 18–80 - NCT04247672Recruiting
Study of knee replacement outcomes using a specific knee implant
This study follows people who need knee replacement for “end-stage” knee osteoarthritis and will receive a specific knee implant system as part of routine care. It aims to measure how well the knee replacement works for patients over time, which may help improve future care.
Hoofddorp, North HollandAges 21–90 - NCT04334031Recruiting
Hospital follow-up study for immune-related disease
This is a study that follows people with an immune-related illness at Lille University Hospital to better understand their care needs over time. By collecting information regularly, the study may help improve how future patients are monitored and treated.
LilleAges 18 years+ - NCT04354649RecruitingPhase 2
Test triage and treatment for immune-related arthritis from immunotherapy
This trial studies how doctors assess and manage immune-related arthritis or joint pain that happens after PD-1/PD-L1 cancer immunotherapy (sometimes with CTLA-4). It may help people get faster, more targeted care while monitoring safety.
Edmonton, AlbertaAges 18 years+ - NCT04529798Recruiting
Testing outcomes after reverse shoulder replacement with a SMR implant
This study looks at how well a type of shoulder replacement (reverse shoulder arthroplasty) works for people with shoulder arthritis. It may help improve understanding of expected results and safety with a specific stemless implant called SMR.
Basel, Canton of Basel-CityAges 18 years+ - NCT04538053RecruitingPhase 4
Simpler antibiotics for uncomplicated bone and joint infections in children
This trial looks at whether a simpler antibiotic plan can work for children with uncomplicated bone or joint infections that start in the community. It may help reduce the need for complicated treatment while still keeping the infection under control.
Kingswood, New South WalesAges 1–18 - NCT04800289Recruiting
Joint skin and joint clinic satisfaction and impact study
This study looks at how patients feel about a combined skin-and-joint doctor visit and whether that visit helps. It mainly involves people who attend the hospital’s joint rheumatologist/dermatologist consultation.
Le MansAges 18 years+ - NCT04846959Recruiting
Pregnancy outcomes study for people exposed to risankizumab
This study looks at pregnancy outcomes in people who took risankizumab during pregnancy (or shortly before getting pregnant). It compares them with pregnancies exposed to similar biologic medicines, to better understand risks and what to expect.
Morrisville, North CarolinaAges Any age - NCT04902807Recruiting
Tool to help decide diagnosis and treatment in immune disorders
This trial tests a tool (a way of collecting health information) to help doctors make better diagnosis, prognosis, and treatment decisions for children with certain immune problems. It also includes healthy children (like relatives) as comparison groups, to see how well the tool works.
ParisAges 1–18 - NCT04955899Recruiting
Testing a device that stimulates the spleen in rheumatoid arthritis
This trial studies whether splenic stimulation (using a medical device to stimulate the spleen) is safe for people with active rheumatoid arthritis. It may help some patients who have not improved enough after at least two other advanced arthritis medicines.
AmsterdamAges 22–75 - NCT04984291Recruiting
Study of shoulder replacement implants for eligible adults
This trial looks at a specific shoulder replacement implant and follow-up care for people who need a shoulder arthroplasty (shoulder replacement) for certain joint problems or fractures. You may be a candidate if you can take part in required visits and your shoulder muscles and bone are suitable.
Irvine, CaliforniaAges 20 years+ - NCT04985435RecruitingPhase 4
Choice-based trial of RA medicines with filgotinib or TNFi
This Phase 4 study compares two treatment options for rheumatoid arthritis (RA): filgotinib or a TNF inhibitor (TNFi). It is designed for adults whose current “standard” RA tablets have not worked well or were not tolerated, to see which approach improves RA control.
LeeuwardenAges 18–101 - NCT05003310Recruiting
Splenic stimulation study for active rheumatoid arthritis
This study tests a treatment that stimulates the spleen to help calm symptoms of active rheumatoid arthritis (RA). It’s mainly for people whose RA has not improved enough after several newer arthritis medicines.
Anniston, AlabamaAges 22–75 - NCT05003934RecruitingPhase 1
IV stem cell treatment safety study for rheumatoid arthritis
This Phase 1 trial tests how safe an intravenous (through a vein) stem cell product is for people with rheumatoid arthritis. It is mainly looking for side effects and safety rather than proving it works yet.
St John'sAges Any age - NCT05007340Recruiting
ILD and autoimmune conditions registry and sample storage
This study collects health information and may store blood or other samples to learn more about interstitial lung disease (ILD) and autoimmune-related conditions. Joining could help researchers understand different causes of ILD and improve future care.
Montreal, QuebecAges 18 years+ - NCT05067998Recruiting
Natural medicine and vitamin IV study for overall health
This study looks at whether natural medicine, vitamin IV fluids, and supplements can help people maintain good health. There don’t appear to be specific eligibility limits listed, so many people may be able to join, but you’d still need screening by the study team.
Dover, DelawareAges 21–80
Hear when a new Arthritis trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 552 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.