Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 553 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05067998Recruiting
Natural medicine and vitamin IV study for overall health
This study looks at whether natural medicine, vitamin IV fluids, and supplements can help people maintain good health. There don’t appear to be specific eligibility limits listed, so many people may be able to join, but you’d still need screening by the study team.
Dover, DelawareAges 21–80 - NCT05147675RecruitingPhase 1
Testing cord stem cell treatment for osteoarthritis safety
This early study (Phase 1) checks whether an infused stem cell product made from donated umbilical cord tissue is safe in people with osteoarthritis. It’s mainly looking for side effects and whether the treatment can be given safely.
St John'sAges Any age - NCT05227924Recruiting
Testing safety and performance of a hip implant device type
This study checks how safe and well a specific brand of hip implant (SYMBOL range) works in people getting a total hip replacement. It may help by confirming the device performs as expected for primary or revision surgeries.
BeaumontAges 18 years+ - NCT05277025Recruiting
Brain pain testing in long-term joint pain and fibromyalgia
This study looks at how the brain processes pain in people with long-term pain conditions like fibromyalgia and rheumatoid arthritis. You may be asked to undergo pain-related tasks to help researchers understand differences between inflammatory and non-inflammatory chronic pain.
Gainesville, FloridaAges 18–70 - NCT05278520Recruiting
Study of hip arthritis types during hip replacement surgery
This study looks at differences inside the hip joint and in body cells when people have hip arthritis or rheumatoid arthritis and receive a hip replacement. Researchers hope this can improve understanding and future treatments for these conditions.
Turku, Southwest FinlandAges 18–74 - NCT05302934Recruiting
Testing a knee-surgery app and sensor after knee replacement
This trial checks whether a data platform that uses a wearable sensor and a phone app works well for people getting a total knee replacement. It may help make follow-up care more organized and easier by capturing recovery information.
Konstanz, Baden-WurttembergAges 18 years+ - NCT05307809Recruiting
Testing inflammation markers in psoriasis with and without joint symptoms
This study looks at how inflammatory “cytokines” are expressed in people with psoriasis—both those with joint involvement and those without. It may help researchers understand what drives joint disease and guide better future monitoring or treatments.
PoitiersAges 18–100 - NCT05310799Recruiting
Personalized risk estimates for children with newly diagnosed JIA
This study looks at how best to estimate a child’s likely symptoms and treatment response in the first phase after a new JIA diagnosis. It may help families and clinicians make clearer, more personalized decisions about care.
Vancouver, British ColumbiaAges 1–18 - NCT05440422RecruitingPhase 2
Anifrolumab to improve blood vessel risk markers in lupus
This Phase 2 trial tests anifrolumab, a lupus medicine, to see if it can improve blood vessel “risk markers” in people with systemic lupus erythematosus (SLE). The study is especially focused on SLE-related problems that can affect heart and blood vessel health.
Bethesda, MarylandAges 18–80 - NCT05487053Recruiting
Nerve block type test after knee replacement
This study compares two pain-control methods for the leg after a total knee replacement: a single injection versus a continuous nerve-block catheter. It aims to see which option helps people recover and do rehab better.
MoscowAges 18 years+ - NCT05507723Recruiting
Smartphone-guided tight gout control vs usual care
This study tests whether a “tighter” gout treatment plan guided through a smartphone app can reduce gout flare-ups compared with usual care. It may help people whose uric acid levels are still high despite treatment.
EdinburghAges 18 years+ - NCT05533372RecruitingPhase 1
Early safety study of IA-14069 in rheumatoid arthritis
This Phase 1 study tests how safe and tolerable IA-14069 is. It includes people with rheumatoid arthritis (RA) and healthy volunteers, and may help researchers plan future RA treatments.
Lenexa, KansasAges 18–70 - NCT05567198Recruiting
Testing hormone shots to protect ovaries during lupus chemotherapy
This study looks at whether a monthly/3-month hormone medicine (a “GnRH shot”) can help protect ovaries in people with lupus who are treated with cyclophosphamide. It also compares this to lupus patients who do not receive the ovarian-protecting shot, using questionnaires to track outcomes.
Bethesda, MarylandAges 18–120 - NCT05596591Recruiting
Shockwave treatment for knee arthritis pain with MRI-confirmed lesions
This trial tests whether focused shockwave therapy (a non-surgical treatment) can reduce knee arthritis pain. It specifically targets people whose MRI shows a small bone problem in one area of the knee.
Cedar Knolls, New JerseyAges 30–80 - NCT05626348RecruitingPhase 4
Test immune-modulator treatments for rheumatoid arthritis with knee trouble
This Phase 4 trial studies whether immune-modulator medicines improve symptoms and function in people with rheumatoid arthritis who have knee problems. It may also compare responses in osteoarthritis and healthy volunteers, depending on the group you fit.
Jinan, ShandongAges 18–80 - NCT05666167Recruiting
Telehealth exercise program for knee or hip arthritis pain
This trial tests whether a structured exercise program delivered by video (telehealth) can help Veterans with painful knee or hip osteoarthritis (arthritis that wears down joints). It may be a good fit if you are not currently very active and can safely join a group program from home.
Aurora, ColoradoAges 18 years+ - NCT05669833RecruitingPhase 3
Guselkumab versus golimumab for active psoriatic arthritis
This Phase 3 study compares two biologic medicines—guselkumab and golimumab—to see which works better for people with active psoriatic arthritis. It is designed for people whose psoriatic arthritis did not respond well to a prior “TNF-blocking” medicine (or lost response).
Loxahatchee Groves, FloridaAges 18–80 - NCT05700682Recruiting
MRI-guided artery blockage procedure for long-term joint pain
This study tests whether an MRI scan that looks at blood flow can help target a joint embolization procedure to reduce chronic shoulder, hip, or knee pain. It first uses MRI to find signs of increased blood flow, then may use the findings to guide treatment if you qualify.
Palo Alto, CaliforniaAges 25–80 - NCT05738824Recruiting
Study how inflammatory muscle diseases naturally change over time
This study follows people with suspected or confirmed inflammatory muscle disease (and sometimes healthy adults) to better understand how the condition progresses and what changes over time. It may help researchers identify patterns that could guide future treatments.
Bethesda, MarylandAges 2–120 - NCT05754190Recruiting
Smartphone study of mood and symptoms in people with pain
This study uses a smartphone app to track daily pain and mood changes over about 4 months. It’s meant to learn patterns that could help better understand how mood and pain affect each other.
Providence, Rhode IslandAges 18 years+ - NCT05796908Recruiting
Prosthesis surgery for unstable elbow joint injuries
This study tests a new implant (prosthesis) for people with a painful, unstable proximal radial/ulna joint in the elbow. It may help restore stability and motion if you are a good surgical candidate and can follow a long recovery and follow-up plan.
Carmel, IndianaAges 18–85 - NCT05818774Recruiting
Different types of neck nerve ablation for chronic pain relief
This trial compares two ways of using radiofrequency heat to treat a specific set of neck pain nerves (the “cervical medial branch nerves”). It may help people with long-lasting neck pain who did not improve with standard treatments and who respond to diagnostic nerve blocks.
Toronto, OntarioAges 18–85 - NCT05835518Recruiting
Study of Adalloce safety and effects in rheumatoid or ankylosing arthritis
This is an observational study that follows people with rheumatoid arthritis (RA) or ankylosing spondylitis (AS) who are planning to start Adalloce. It aims to understand how safe the medicine is and how well it works in real-world care.
DaeguAges 19–74 - NCT05848622Recruiting
Gait retraining after ACL surgery for fast knee recovery
This trial tests a walking (gait) rehabilitation program to improve how you move after ACL reconstruction. It may help if you are still having walking mechanics issues in the months to years after surgery.
Chapel Hill, North CarolinaAges 16–35
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 553 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.