Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 554 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07313020Enrolling by invitationEarly Phase 1
Handheld imaging to track stem cells in knee osteoarthritis
This trial tests a new handheld imaging device (MPI) to track stem cells injected into the knee. It aims to see if the device can safely monitor how the stem cells move and work in people with knee osteoarthritis.
Haikou, HainanAges 18–75 - NCT06385275RecruitingPhase 1/Phase 2
Vitamin K for Knee Osteoarthritis
This study tests whether taking vitamin K can help with knee osteoarthritis pain and joint health. It is for older adults who have knee OA and are not on blood thinners.
Boston, MassachusettsAges 50 years+ - NCT06876350Recruiting
Wood cast vs. thermoplastic splint after thumb surgery
This trial compares two types of casts used after thumb joint replacement surgery to see which one works better for recovery. Participation lasts about 6 weeks.
Tampa, FloridaAges 18 years+ - NCT07555067Enrolling by invitation
Robotic Knee Replacement Surgery Comparison
This trial compares two different robotic systems used during knee replacement surgery for knee arthritis (wear and tear). The study helps doctors understand which robotic system may provide better results.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT03839758Recruiting
Personalized implant study for shoulder arthritis
This study looks at a personalized implant/instrument setup for people having shoulder replacement due to wear-and-tear arthritis (and bone tissue death). It aims to see whether customizing the surgery approach improves outcomes over time, including up to 2 years.
Montreal, QuebecAges 18–99 - NCT06685120Recruiting
PRP and hyaluronic acid for knee osteoarthritis
This study tests a combination of platelet-rich plasma (PRP) and hyaluronic acid injections for knee osteoarthritis. It aims to see if these injections together can reduce pain and improve function better than standard treatments.
BolognaAges 40–75 - NCT06522152Recruiting
Long-term outcomes after meniscal transplant
This study looks at how well patients' knees are doing 10 years or more after a meniscal transplant (a surgery to replace torn knee cartilage). It aims to understand the long-term benefits and any changes in knee function.
BolognaAges 18–65 - NCT06231758RecruitingPhase 3
Metformin for knee osteoarthritis: a phase 3 trial
This study tests whether metformin, a common diabetes medication, can help reduce pain and improve knee function in people with knee osteoarthritis. It may offer a new treatment option for those with moderate knee OA.
Damietta, New DamiettaAges 30–60 - NCT07377669Enrolling by invitation
Partial knee replacement plus ACL repair study
This study tests a combination surgery: repairing the torn ACL at the same time as replacing only the damaged part of your knee. It's designed for active people with arthritis in one knee compartment and a fully torn ACL.
BolognaAges 18–75 - NCT06118892Recruiting
Knee implant study for inner knee pain from arthritis
This trial is testing a new knee implant designed to relieve pain on the inner side of the knee caused by osteoarthritis. It is for people who have not gotten enough relief from other treatments like physical therapy or injections.
Sonoma, CaliforniaAges 25–65 - NCT06130956Recruiting
Vegan diet before knee replacement surgery study
This study compares a 2-week vegan diet to a regular diet before knee replacement surgery. It looks at how the diet affects protein turnover in the knee joint.
ArnhemAges 60–80 - NCT06319911Recruiting
Testing a new shoulder replacement implant system
This study tests a new shoulder implant system for people who need their first shoulder replacement due to arthritis or a shoulder deformity. It helps researchers see how well the implant works and if it improves shoulder function and pain.
San Francisco, CaliforniaAges 18 years+ - NCT07544576Enrolling by invitationPhase 4
Knee Arthritis Injection: Two Injection Methods Compared
This study compares two ways of injecting a steroid medication into arthritic knees: using landmark guidance (traditional method) with a higher dose versus ultrasound guidance (imaging) with a lower dose. The goal is to see which approach works better to reduce knee pain and improve function.
Ventura, CaliforniaAges 50 years+ - NCT06407427Recruiting
Mobile app for recovery after hip, knee, or spine surgery
This study tests whether a mobile app can help with physical therapy after common bone or joint surgeries. You may qualify if you recently had a hip fracture, hip or knee replacement, or spine surgery without paralysis. The app guides your exercises at home.
New Haven, ConnecticutAges 18 years+ - NCT06982105RecruitingPhase 4
Comparing two antibiotics for children with MRSA bone or head infections
This study compares two oral antibiotics, TMP-SMX and clindamycin, to see which works better for children with MRSA infections in bones, joints, or head/neck areas. It aims to find the best treatment after initial IV therapy.
Indianapolis, IndianaAges 2 months–18 years - NCT07118501Recruiting
Study of the Incompass total ankle system
This study is testing a new ankle replacement device called Incompass. It aims to see how well the device works and how safe it is for people who need ankle replacement surgery.
Morton Grove, IllinoisAges 21 years+ - NCT06712628Recruiting
Comparing how long people stay on upadacitinib vs TNF inhibitors for RA
This study compares how well people with rheumatoid arthritis stay on two types of medicines: upadacitinib (Rinvoq) and TNF inhibitors. It looks at real-world experiences in Germany to see if one medicine is more likely to be continued over time.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT07201558RecruitingPhase 1
Surovatamig safety study for rheumatoid arthritis or lupus
This trial tests surovatamig, a new experimental treatment, to see if it's safe and how the body processes it in adults with moderate-to-severe rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE). It may be an option if you've tried other biologic or targeted therapies without success.
Birmingham, AlabamaAges 18–65 - NCT07731737Recruiting
Biofeedback vs foam roller for knee osteoarthritis
This trial compares two non-surgical therapies—pressure biofeedback and foam rolling—to see which better reduces pain, improves muscle function, and boosts quality of life in people with early-stage knee osteoarthritis.
LahoreAges 45–65 - NCT07295847RecruitingPhase 1
Study of AZD0120 for autoimmune diseases
This trial tests if a new medication, AZD0120, is safe for people with autoimmune diseases. It aims to help patients by targeting the immune system.
Tucson, ArizonaAges 18–75 - NCT07504887Recruiting
Aerobic Exercise for Rheumatoid Arthritis
This study tests whether a program of aerobic exercise (like walking or cycling) can help women with mild rheumatoid arthritis feel better and move easier. You would do supervised exercise sessions and be checked for changes in your symptoms and overall health.
KütahyaAges 30–70 - NCT04833465Recruiting
Testing a new outcome measure in kids with rheumatology diseases
This study looks at how to measure treatment success in children with juvenile idiopathic arthritis (JIA), lupus (SLE), or fibromyalgia (FM). It may help doctors track symptoms more reliably over time.
Washington D.C., District of ColumbiaAges 5–21 - NCT06570798RecruitingPhase 2
Testing Two Drugs for Lupus and Rheumatoid Arthritis
This trial tests two study drugs, inebilizumab and blinatumomab, for people with lupus (SLE) or rheumatoid arthritis (RA) that hasn't gotten better with standard treatments. It focuses on those with active disease, especially lupus-related kidney problems.
Scottsdale, ArizonaAges 18–75 - NCT07712939RecruitingPhase 1
Study of CND319 for rheumatic diseases
This study tests a new drug called CND319 in healthy volunteers and people with rheumatoid arthritis or Sjögren's disease. The goal is to see if it is safe and how the body responds to it.
Melbourne, VictoriaAges 18–65
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 554 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.