Clinical trials
Arthritis clinical trials
Below are recruiting arthritis clinical trials, each written for real people, not researchers. We’re tracking 539 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06786936Recruiting
Study of IL-17 in depression with psoriasis
This study explores whether a protein called IL-17 might link skin/joint inflammation with depressive symptoms. If you have psoriasis or psoriatic arthritis and are starting a specific biologic (secukinumab, bimekizumab, or ixekizumab), this could help understand how treatment affects your mood.
Glasgow, ScotlandAges 18–74 - NCT06906939RecruitingEarly Phase 1
Brain stimulation and tai chi for knee arthritis and depression
This pilot study tests if combining brain stimulation (rTMS) with Tai Chi can help knee arthritis pain and improve depression. It compares these two treatments to see which works better for people with both pain and low mood.
Los Angeles, CaliforniaAges 50–95 - NCT06888193RecruitingPhase 1
Bimekizumab in breast milk of mothers being treated
This study measures how much bimekizumab (Bimzelx) gets into breast milk. It helps us understand if the medicine is safe for breastfeeding babies whose mothers take this drug.
Santa Monica, CaliforniaAges 18 years+ - NCT06888960RecruitingEarly Phase 1
Testing CC312 for people with autoimmune diseases
This early-phase study tests a new drug called CC312 in patients with certain autoimmune diseases like lupus, myositis, scleroderma, rheumatoid arthritis, immune thrombocytopenia, or autoimmune hemolytic anemia. The goal is to see if it's safe and how the body handles it.
Tianjin, ChinaAges 18 years+ - NCT06876350Recruiting
Wood cast vs. thermoplastic splint after thumb surgery
This trial compares two types of casts used after thumb joint replacement surgery to see which one works better for recovery. Participation lasts about 6 weeks.
Tampa, FloridaAges 18 years+ - NCT06870045Recruiting
Walking ability test in children with JIA
This study looks at how well children with JIA (arthritis in one knee) can walk and balance, using a simple test called the Dynamic Gait Index. It aims to find a better way to measure walking problems in kids with JIA.
Istanbul, TurkeyAges 8–16 - NCT04095637Recruiting
Compare two types of partial knee replacement surgeries
This study compares two implant types used for a partial knee replacement (only the inside/medial part) for people with “wear-and-tear” arthritis in that compartment. It looks to see which option leads to better outcomes after surgery and follow-up.
LondonAges 40–80 - NCT06838143Recruiting
Ilaris real-world study for periodic fevers and sJIA
This study watches how people with certain periodic fever syndromes or a severe type of childhood arthritis (sJIA) do on the medicine Ilaris during their regular doctor visits. It collects information to see how well the medicine works in everyday care.
SeoulAges 2–100 - NCT06259890Recruiting
Salt intake and arthritis study
This study tests whether the amount of salt you eat affects inflammation and symptoms in people with certain types of arthritis (ankylosing spondylitis or psoriatic arthritis). You will be asked to follow a specific sodium diet and have some checkups to see how your arthritis responds.
BesançonAges 18–80 - NCT04846959Recruiting
Pregnancy outcomes study for people exposed to risankizumab
This study looks at pregnancy outcomes in people who took risankizumab during pregnancy (or shortly before getting pregnant). It compares them with pregnancies exposed to similar biologic medicines, to better understand risks and what to expect.
Morrisville, North CarolinaAges Any age - NCT06801119RecruitingPhase 1
HN2301 for autoimmune diseases study
This trial tests a new mRNA treatment called HN2301 for people with autoimmune diseases like lupus, scleroderma, or rheumatoid arthritis. It aims to see if the treatment is safe and helps control the disease.
Hefei, AnhuiAges 18–69 - NCT06788717Enrolling by invitation
Study on Hip Revision Stem Performance
This study is checking how well a specific hip implant (the Comprehensive Revision Stem) works in people who need hip replacement. It helps make sure the implant is safe and effective over time.
Los Angeles, CaliforniaAges 18–100 - NCT06782529RecruitingPhase 4
Knee injection study for patients with obesity and arthritis
This study tests if steroid injections for knee arthritis work in people with obesity. It may help you manage pain and avoid surgery.
Jacksonville, FloridaAges 55–85 - NCT06775704Recruiting
Studying outcomes of the ROMAX hip resurfacing system
This study tracks how well the ROMAX hip resurfacing system works over time, focusing on patient recovery and X-ray results. It is designed for adults who need hip resurfacing and are generally healthy enough for surgery.
LilleAges 18–65 - NCT06781463Recruiting
Knee arthritis treatment registry
This study tracks patients with knee arthritis who undergo a procedure called genicular artery embolization (GAE), a minimally invasive option for those not ready for or not eligible for knee replacement. The goal is to see how well GAE works for pain relief.
Chicago, IllinoisAges 18 years+ - NCT06733935RecruitingPhase 1/Phase 2
Study of NKX019 for immune diseases
This trial tests an investigational cell therapy called NKX019 for people with certain autoimmune diseases like scleroderma, myositis, vasculitis, or rheumatoid arthritis. It aims to see if NKX019 can help control the disease when standard treatments have not worked well enough.
Orange, CaliforniaAges 18–75 - NCT06735027Recruiting
Steroid shot vs nerve block for shoulder arthritis
This trial compares two kinds of injections for shoulder pain caused by arthritis or rotator cuff problems. The goal is to see which one works better for pain relief.
Minneapolis, MinnesotaAges 18–99 - NCT06712628Recruiting
Comparing how long people stay on upadacitinib vs TNF inhibitors for RA
This study compares how well people with rheumatoid arthritis stay on two types of medicines: upadacitinib (Rinvoq) and TNF inhibitors. It looks at real-world experiences in Germany to see if one medicine is more likely to be continued over time.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+ - NCT05700682Recruiting
MRI-guided artery blockage procedure for long-term joint pain
This study tests whether an MRI scan that looks at blood flow can help target a joint embolization procedure to reduce chronic shoulder, hip, or knee pain. It first uses MRI to find signs of increased blood flow, then may use the findings to guide treatment if you qualify.
Palo Alto, CaliforniaAges 25–80 - NCT04985435RecruitingPhase 4
Choice-based trial of RA medicines with filgotinib or TNFi
This Phase 4 study compares two treatment options for rheumatoid arthritis (RA): filgotinib or a TNF inhibitor (TNFi). It is designed for adults whose current “standard” RA tablets have not worked well or were not tolerated, to see which approach improves RA control.
LeeuwardenAges 18–101 - NCT06687551RecruitingPhase 4
Testing lower doses of JAK inhibitors for rheumatoid arthritis
This study tests whether people with rheumatoid arthritis whose disease is well controlled can safely take a lower dose of their JAK inhibitor medication. It aims to see if reducing the dose still keeps inflammation down and prevents flare-ups.
Toulouse, OccitanieAges 18–65 - NCT06685120Recruiting
PRP and hyaluronic acid for knee osteoarthritis
This study tests a combination of platelet-rich plasma (PRP) and hyaluronic acid injections for knee osteoarthritis. It aims to see if these injections together can reduce pain and improve function better than standard treatments.
BolognaAges 40–75 - NCT06670651Enrolling by invitation
Study of a new total knee replacement system
This trial is testing a new knee replacement system called LinkSymphoKnee. It is for people needing a first-time total knee replacement to help reduce pain and improve function.
Birmingham, AlabamaAges 18–79 - NCT03938701RecruitingPhase 2
Imaging gut and joint inflammation with adalimumab and a light tracer
This study uses a special “light tracer” medicine with adalimumab to see where inflammation is in the gut (IBD) or joints (RA). If you have active disease, it may help doctors better target treatment by showing inflammation more clearly during scans.
Groningen, Provincie GroningenAges 18 years+
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Common questions
- Are there clinical trials for arthritis?
- Yes. Clin2 currently lists 539 recruiting arthritis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a arthritis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a arthritis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.