Clinical trials
Augmentation clinical trials
Below are recruiting augmentation clinical trials, each written for real people, not researchers. We’re tracking 289 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05317403RecruitingPhase 1
Venetoclax plus chemo to change cancer cell behavior
This Phase 1 trial tests whether venetoclax, combined with chemotherapy and a “cancer cell behavior” medicine strategy, can improve treatment for people with AML that has come back or not gone into remission. It’s mainly looking at safety and early signs of benefit.
Milwaukee, WisconsinAges 1–25 - NCT05412758Recruiting
Breath and blood tests to study stomach and food-pipe cancer
This study looks at how certain “volatile” substances in breath change in people with stomach or food-pipe (oesophageal) cancer, compared with people who have other non-cancer stomach/food-pipe conditions. It may help researchers find better, earlier ways to assess cancer—especially in people who have not started treatment yet.
LondonAges 18–90 - NCT05415631Recruiting
AI helps detect bladder tumors during bladder exam
This study tests an artificial-intelligence (AI) system during real-time bladder evaluation to better spot bladder tumors. It may help your care team find tumors more accurately during diagnosis or follow-up.
AmiensAges 18 years+ - NCT05541250RecruitingPhase 1
Stem-like nerve cell treatment for severe nerve injuries
This Phase 1 study tests whether adding a patient’s own nerve support cells to a severely injured nerve is safe and helpful. It’s for people with recent major nerve damage in an arm or leg, with strict safety checks.
Miami, FloridaAges 18–65 - NCT05644301RecruitingPhase 3
Blood-marker guided add-on treatment for major depression
This study tests whether doctors can choose the best add-on immune-related treatment for people with major depressive disorder by using inflammation blood tests. It’s meant for people whose depression has not improved enough with their current antidepressant.
Duffel, AntwerpenAges 18–65 - NCT05646394Recruiting
Registry for blood-clot prevention plans in arterial antiphospholipid syndrome
This study keeps a registry to follow people with antiphospholipid syndrome (APS) who have had arterial blood clots (like stroke). It collects information about the treatment approach your clinician chooses to see how different antithrombotic regimens may perform and be tolerated.
Buenos Aires, Buenos Aires F.D.Ages 18 years+ - NCT05653518Recruiting
Artificial pancreas therapy to steady sugars and protect the heart
This study tests an “artificial pancreas” system that automatically helps control insulin to reduce wide swings in blood sugar. It also aims to see whether steadier sugars can improve heart health in adults with type 1 diabetes.
Charlottesville, VirginiaAges 18–40 - NCT05681780RecruitingPhase 1
CD40L-treated immune cells for advanced lung cancer with certain gene changes
This Phase 1 study tests a lab-made immune cell treatment (TIL) boosted with CD40L, plus nivolumab, for stage IV or returning non-small cell lung cancer with specific gene changes (EGFR, ALK, ROS1, or HER2). It aims to help your immune system attack the cancer after it has grown despite standard treatments.
Tampa, FloridaAges 18 years+ - NCT05682677Recruiting
Brain stimulation plus cognitive training for depression after mild head injury
This study tests whether a combination of brain stimulation and cognitive training can reduce depression symptoms in people who have ongoing mild traumatic brain injury (TBI). It may help by targeting both mood and thinking/processing skills affected after mTBI.
La Jolla, CaliforniaAges 18–65 - NCT05698446Recruiting
Compare ankle surgery options for lateral ankle instability
This study compares different surgical techniques to treat ongoing (chronic) pain and instability on the outside of the ankle. If you qualify, your care team will determine which surgery approach best fits your situation and then track your outcomes.
BeijingAges 18–60 - NCT05739331Recruiting
AI-assisted breathing test to check swollen chest lymph nodes
This trial uses an AI-supported breathing procedure to help doctors examine enlarged lymph nodes in the chest when the cause is still unknown. It may help improve how accurately and efficiently doctors assess these lymph nodes so you can get answers sooner.
LevangerAges 18 years+ - NCT05759468RecruitingPhase 2
Add NAD to help protect kidneys in diabetes
This Phase 2 study tests whether adding NAD can improve kidney health in people with diabetes-related kidney disease. It is designed for people with certain urine lab results showing kidney stress, while keeping blood sugar and safety limits within range.
Boston, MassachusettsAges 30 years+ - NCT05855759Recruiting
New graft to help repair large rotator cuff tears
This trial studies a special “acellular” (cell-free) skin-derived graft combined with healing-stimulating materials to improve healing and function after surgery for large rotator cuff tears. It may help people with serious tendon damage in the shoulder, but only if their tear type and health situation fit the study rules.
Bologna, BOAges 18–65 - NCT05906004Recruiting
Follow-up study after Pitch-Patch shoulder repair
This study checks how well a Pitch-Patch device is doing to support the rotator cuff (a shoulder tendon). It enrolls people who had the device placed about 2 to 2.5 years ago so the researchers can follow outcomes and safety over time.
ReadingAges 16 years+ - NCT05953051Recruiting
ACL surgery with a tunnel widened using enriched bone
This trial compares two techniques for ACL reconstruction—one uses an enriched, patient’s own bone during surgery and the other uses the standard approach. It may help researchers understand whether the enriched bone method improves knee healing and function.
ZurichAges 18–50 - NCT05960747Recruiting
Training for thoracentesis using an augmented reality simulator
This study tests whether a specific training using an augmented reality (AR) simulator helps medical students perform thoracentesis more safely and effectively. It also involves patients getting a first-time thoracentesis as part of routine care.
Strasbourg, Bas-RhinAges 18 years+ - NCT05997381Recruiting
BioBrace implant for rotator cuff tear repair
This study tests a new implant called BioBrace to help repair full-thickness rotator cuff tears during shoulder surgery. It may be a good option if you have a moderate-sized tear, have already tried non-surgical treatments, and are between 40 and 70 years old.
New Haven, ConnecticutAges 40–70 - NCT06194851RecruitingPhase 2
Oxytocin nasal spray plus couples therapy for Veterans with PTSD
This study tests whether a nasal spray of oxytocin (a natural hormone) can boost the effects of a brief couples therapy for Veterans with PTSD. You and your partner would receive either the spray or a placebo (inactive spray) during therapy sessions to see if it helps reduce PTSD symptoms and improve relationship satisfaction.
San Diego, CaliforniaAges 18 years+ - NCT06225245Recruiting
Spinal cord stimulation for arm recovery
This study tests whether a device placed on the spinal cord (called an epidural stimulator) can help improve arm and hand function in people with chronic spinal cord injuries. The goal is to boost nerve activity and make rehabilitation more effective.
Houston, TexasAges 22–65 - NCT06282224Recruiting
Augmented reality for skull base surgery through the nose
This study tests whether using an augmented reality (AR) navigation system can help surgeons perform skull base surgery through the nose more accurately. If you are already planning this type of surgery and have had the required scans, you may be eligible.
Xiamen, FujianAges Any age - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT06318559Recruiting
3D augmented reality vs. standard robot prostate surgery
This trial tests whether adding a 3D augmented-reality model to standard robot-assisted prostate surgery can help doctors remove the cancer while better preserving sexual function. It is for men whose MRI shows the cancer may have slightly spread outside the prostate.
Candiolo, TurinAges 40–99 - NCT06367582Recruiting
Study of Teknimed spine cements outcomes
This study is checking how well certain spine cements (used to stabilize broken vertebrae) work in real life. If you are 18 or older and have had or will have a TEKNIMED cement procedure, you may be able to join.
Strasbourg, Bas-RhinAges 18 years+ - NCT06381674Recruiting
Wearable tech for balance rehab after concussion
This study tests whether a wearable device can help people with balance and vision problems after a mild concussion. You will use the device to guide your own exercises and help improve your recovery.
Portland, OregonAges 18–60
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Common questions
- Are there clinical trials for augmentation?
- Yes. Clin2 currently lists 289 recruiting augmentation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a augmentation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a augmentation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.