Clinical trials · Boston, MA
BRCA2 Mutation clinical trials in Boston
We’re tracking 6 recruiting brca2 mutation studies with a site in or near Boston — including Phase 1 and Phase 1/Phase 2 studies, each written for real people, not researchers.
Recruiting studies near Boston
- NCT06488378RecruitingPhase 1
Axatilimab and olaparib for BRCA/PALB2-mutated breast cancer
This trial tests combining two drugs – axatilimab and olaparib (a PARP inhibitor) – for people with advanced HER2-negative breast cancer that carries a BRCA or PALB2 gene mutation. The goal is to see if this new combination is safe and effective.
Boston, MassachusettsAges 18 years+ - NCT06395519RecruitingPhase 1/Phase 2
Study of ETX-19477 for advanced solid tumors
This trial tests an experimental drug called ETX-19477 for people with advanced solid tumors that have stopped responding to other treatments. It aims to see if the drug is safe and effective, especially for those with certain genetic changes (BRCA2 mutations).
Boston, MassachusettsAges 18 years+ - NCT03544983Enrolling by invitation
Genetic education program for BRCA family members
This trial offers education about BRCA1 and BRCA2 gene mutations to help families understand testing, cancer risk, and next steps. It may be helpful if you are a family member of someone who recently learned they have a BRCA mutation.
Boston, MassachusettsAges 21–75 - NCT04294927Recruiting
Tube removal first, then ovaries later for high-risk women
This study looks at whether removing the fallopian tubes first, and the ovaries later, is safe for women with certain inherited gene mutations that raise ovarian cancer risk. It may help you understand a prevention approach when you’re considered high risk and have finished having children.
Boston, MassachusettsAges 25–50 - NCT04150042RecruitingPhase 1
Test of chemotherapy plus your own stem cells for metastatic cancer
This Phase 1 trial tests a treatment approach using standard chemotherapy along with stem cells taken from you to treat metastatic pancreatic or breast cancer. It is mainly designed to check safety and find the best way to give the treatment, and it may offer an option for people whose cancer has spread.
Boston, MassachusettsAges 18 years+ - NCT05129605Recruiting
Prostate cancer genetic risk screening study for men
This study looks at your personal and family risk for prostate cancer and helps decide who should have extra screening like MRI. It may help you find cancer earlier if you are at higher genetic risk.
Boston, MassachusettsAges 35–74
Hear when a new BRCA2 Mutation trial opens near Boston, MA
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BRCA2 Mutation trials in other cities
Where these studies are running near Boston
Institutions with a site for the recruiting brca2 mutation studies listed above.
- Dana-Farber Cancer Institute · 3 studies
- Massachusetts General Hospital · 3 studies
- Beth Israel Deaconess Medical Center
- Brigham and Women's Hospital
What taking part in a brca2 mutation study involves
A screening visit first
Before anything else, the study team checks whether you fit — usually a visit with some tests. You can stop at any point, and screening is typically free.
Care at a nearby site
Study visits happen at a clinic or hospital taking part. Many studies cover the cost of the study treatment and related visits, and some reimburse travel.
You stay in control
Taking part is voluntary and you can leave a study at any time, for any reason, without affecting your regular care.
The team decides eligibility
Our fit check is a helpful first read, not a decision. The study team makes the final call after reviewing your health history.
Looking wider? See all recruiting brca2 mutation studies in Massachusetts.
Common questions
- Are there brca2 mutation clinical trials near Boston?
- Yes. We're currently tracking 6 recruiting brca2 mutation studies with a site near Boston, each rewritten in plain language so you can see what it's testing and who it's for.
- How do I find out if I qualify for a brca2 mutation study near Boston?
- Each study lists its eligibility rules — age, diagnosis, prior treatments. On every trial page we explain these in plain language and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Do I have to live in Boston to take part?
- Not necessarily. These studies have a site near Boston, but eligibility is about your health, not your address — some people travel to take part, and a few studies reimburse travel. The study team can tell you what's required.
- Does it cost anything to join a brca2 mutation trial?
- Using Clin2 is always free. Many trials cover the study treatment and related visits; some reimburse travel. The study team explains exactly what's covered before you decide.
Not the right time?
New brca2 mutation studies open near Boston regularly. Set up a health profile and we’ll quietly watch for studies that fit you and email you when one opens.