Clinical trials
Breast Reconstruction clinical trials
Below are recruiting breast reconstruction clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05846438Recruiting
Drain care check after breast implant surgery
This study looks at whether a specific way of caring for surgical drains can lower infection rates and improve quality of life after breast reconstruction with a tissue expander. You may be asked to follow the study’s drain-care steps during recovery.
Columbia, MissouriAges 18–100 - NCT06080178RecruitingPhase 4
Goal-directed fluids during breast reconstruction surgery
This trial tests a precise fluid management strategy during DIEP flap breast reconstruction to improve outcomes. It aims to reduce complications and improve recovery.
Ghent, East FlandersAges 18–70 - NCT06464913RecruitingPhase 2
Chest wall radiation omission after breast implant reconstruction
This study tests whether skipping chest wall radiation after breast implant reconstruction is safe and effective for patients with stage T1-2N1 breast cancer. It may help avoid side effects from radiation while still controlling the cancer.
Hangzhou, ZhejiangAges 18–70 - NCT04992650Enrolling by invitation
Ultrasound imaging during breast reconstruction after mastectomy and radiation
This study uses ultrasound pictures to better understand blood flow in breast reconstruction sites after a mastectomy, when you also need radiation therapy. It may help improve how clinicians monitor and manage healing and treatment effects in this situation.
Rochester, MinnesotaAges 18 years+ - NCT06711965Recruiting
Custom molds for breast reconstruction shaping
This trial tests custom 3D-printed molds to help shape breast tissue during reconstruction. It is for people who are already planning a DIEP or TRAM flap after mastectomy.
Houston, TexasAges 18 years+ - NCT05412225RecruitingPhase 1
Pre-surgery radiation, then mastectomy and immediate breast reconstruction
This Phase 1 study looks at giving radiation before surgery for people with locally advanced breast cancer, then performing a mastectomy and immediate reconstruction. It aims to see whether this combined approach can shrink the cancer before surgery and safely allow reconstruction afterward.
Basking Ridge, New JerseyAges 18 years+ - NCT05439005RecruitingPhase 3
Opioid-free anesthesia for breast reconstructive flap surgery
This trial compares opioid-free anesthesia with opioid-based anesthesia during breast free-flap reconstruction surgery. It aims to see whether avoiding opioids can improve safety and comfort around the time of surgery.
ParisAges 18 years+ - NCT07658170Recruiting
Fat graft with platelet-rich fibrin for breast reconstruction after lumpectomy
This trial tests using a patient's own fat plus a special blood product (platelet-rich fibrin) to rebuild the breast right after a lumpectomy for breast cancer. It may help improve healing and appearance for women with early-stage, hormone-sensitive breast cancer.
Saint PetersburgAges 18–69 - NCT06903468Recruiting
New cavity marking technique for breast cancer surgery and radiation
This trial tests a new way to mark the area where breast cancer is removed during lumpectomy with oncoplastic reconstruction. The goal is to make follow-up radiation more precise and reduce the need for additional surgeries.
Gainesville, FloridaAges 18 years+ - NCT06024187Recruiting
Cold vs. heat cutting in nipple-sparing mastectomy
This study compares two ways of cutting tissue during nipple-sparing mastectomy (breast removal with nipple preservation) followed by immediate implant reconstruction. One method uses a cold instrument, the other uses heat (electrocautery). The goal is to see which leads to better nipple survival and healing.
Guangzhou, GuangdongAges 18–75 - NCT07127003Recruiting
Surgical bypass to prevent arm swelling after lymph node removal
This study tests a surgical bypass (called ILR) to prevent arm swelling (lymphedema) after removing lymph nodes from under the arm during breast cancer surgery. The goal is to see if this extra step helps keep your arm healthy.
Tampa, FloridaAges 18–75 - NCT06425874Recruiting
Study on how social factors affect well-being after breast surgery
This study looks at how things like income, education, and support systems affect the quality of life and emotional well-being of younger women (ages 18-50) after breast cancer surgery. The goal is to better understand and address these factors.
Guangzhou, GuangdongAges 18–50 - NCT05366699Recruiting
Procedure to help prevent arm swelling after breast surgery
This trial studies a new procedure meant to lower the chance of getting lymphedema (arm swelling) after breast cancer surgery that removes lymph nodes in the armpit. It may help patients reduce the risk of long-term arm swelling, especially after lymph node dissection.
San Francisco, CaliforniaAges 18–75 - NCT06676761Recruiting
Study of a new minimal scar mastectomy
This trial is testing a new surgical technique that leaves a smaller scar during mastectomy for breast cancer. It may be a good option if you want to keep the scar as small as possible.
SingaporeAges Any age
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Common questions
- Are there clinical trials for breast reconstruction?
- Yes. Clin2 currently lists 110 recruiting breast reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Breast Reconstruction After Mastectomy
- Implant Based Breast Reconstruction
- Mastectomy and Breast Reconstruction
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Breast Reconstruction Surgery
- DIEP Flap Breast Reconstruction
- Triple Negative Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.