Clinical trials
Mastectomy and Breast Reconstruction clinical trials
Below are recruiting mastectomy and breast reconstruction clinical trials, each written for real people, not researchers. We’re tracking 96 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07641985Recruiting
Fat grafting for breast reconstruction after cancer and radiation
This study compares two ways to rebuild the breast after mastectomy and radiation using your own tissue: fat grafting alone, or a more complex surgery using abdominal tissue. The goal is to see which method gives better results and quality of life.
Maastricht, LimburgAges 18 years+ - NCT05888571Recruiting
Testing pre-chest breast reconstruction with or without mesh
This study looks at whether adding mesh (a supportive material) improves results in breast reconstruction placed in front of the chest. It may help some people heal better and get a more comfortable shape, but it depends on your surgery plan and health factors.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT06456554Recruiting
Dermal matrix study in breast reconstruction
This trial tests a special supportive material called acellular dermal matrix in women having two-stage breast reconstruction after mastectomy. The goal is to learn how well it works when the implant is placed directly under the skin, over the chest muscle.
Little Rock, ArkansasAges 22 years+ - NCT06027996Recruiting
Melodi Matrix in breast reconstruction
This trial tests a new mesh-like device called Melodi Matrix to support breast reconstruction after mastectomy. It may help women who are planning immediate two-stage implant reconstruction after removing one or both breasts.
Palo Alto, CaliforniaAges 22 years+ - NCT05460780Recruiting
Tissue device study for breast reconstruction after mastectomy
This first-time-in-humans study tests a tissue-engineering chamber called MATTISSE® to help the healing of breast reconstruction using specific tissue flaps after mastectomy for cancer. If you qualify, you would be assessed for safety and how well the reconstructed tissue heals.
Strasbourg, FranceAges 18 years+ - NCT05585710Recruiting
Study pulsed rinse during breast implant reconstruction
This trial tests whether a special “pulsed rinse” technique during implant-based breast reconstruction improves care during surgery. If you’re having immediate expander placement at the time of mastectomy, you may be eligible to try this approach under research oversight.
Birmingham, AlabamaAges 18–75 - NCT05003635Recruiting
Testing a vacuum device to improve breast fat reconstruction
This trial tests whether an external vacuum device (EVEBRA) can help surgeons place fat grafts more effectively during breast reconstruction. You may be able to try the device in an office visit and, if you qualify, receive reconstruction using only your own fat.
Maastricht, LimburgAges 23–69 - NCT04891510Recruiting
Compare fat grafting products in breast surgery
This trial compares three methods for moving your own fat into the breast during breast surgery. It may help improve how well fat grafting works and how surgeons choose the best method for you.
New York, New YorkAges 18 years+ - NCT04661501Recruiting
Trial of special breast skin graft in implant reconstruction
This trial studies whether a lab-made skin graft (called ADM) used with tissue expanders can improve breast reconstruction after mastectomy. It may help people who are planning a specific two-step implant reconstruction approach.
Vancouver, British ColumbiaAges 21–65 - NCT05975359Recruiting
Testing a fluid-drain device during breast implant reconstruction
This study tests a new way to measure and manage fluid drainage during immediate breast reconstruction with implants. It may help surgeons reduce complications and improve the reconstruction experience after mastectomy.
Palo Alto, CaliforniaAges 18–65 - NCT07135596Recruiting
OviTex PRS mesh for breast reconstruction after mastectomy
This study tests a special mesh called OviTex PRS used during immediate breast reconstruction after mastectomy. The goal is to see if it is safe and effective for supporting the new breast implant.
Bowling Green, KentuckyAges 22–75 - NCT06512259Recruiting
AlloMend tissue support in breast reconstruction after mastectomy
This study tests a special tissue support called AlloMend used during breast reconstruction after mastectomy. It helps see how well the tissue works and how patients heal.
Joliet, IllinoisAges 18 years+ - NCT07234461Recruiting
Sexual well-being after mastectomy and reconstruction
This study looks at how mastectomy and breast reconstruction affect a woman's sexual well-being. If you are having a mastectomy for breast cancer or a preventive mastectomy because you are at high risk, you may be able to join.
Bari, ItalyAges 18 years+ - NCT06575192RecruitingPhase 3
Breast reconstruction study with ARTIA matrix
This study tests a new supportive mesh called ARTIA for women having breast reconstruction immediately after a mastectomy. The mesh is placed under the skin to help hold a breast implant in position during a two-stage reconstruction process.
Los Angeles, CaliforniaAges 18 years+ - NCT06013514Recruiting
Study of Nagor Perle breast implants for reconstruction or cosmetic surgery
This study is following people who got Nagor Perle breast implants to see how they perform over time. It includes women getting implants for breast reconstruction, cosmetic augmentation, or revision surgery.
Manchester, United KingdomAges 18–65 - NCT06774352Recruiting
Prosthetic breast reconstruction after mastectomy
This trial studies breast reconstruction using implants after mastectomy (breast removal surgery). It aims to understand how different types of implants work and how patients recover.
BolognaAges 18–70 - NCT06555614Recruiting
Safety of a special mesh in breast reconstruction
This study tests if a special mesh called an acellular dermal matrix (SC DERM® Recon) is safe for women having breast reconstruction with implants after mastectomy for breast cancer. It involves careful follow-up to check for any problems.
Seoul, SeoulAges 19–79 - NCT07679594Recruiting
A study of Luna breast implants for augmentation or reconstruction
This study is testing Eurosilicone Luna breast implants in women who need breast augmentation (enlargement) or reconstruction after mastectomy. It aims to see how safe and effective the implants are over time.
Villefranche-sur-SaôneAges 18–65 - NCT07718425Recruiting
Endoscopic mastectomy surgery study
This study tests a new, less invasive surgery called endoscopic mastectomy for women who need breast removal. It aims to see how well the surgery works, how the breast looks and feels afterward, and whether nipple sensation is preserved.
Ponderano, BIAges 18–75 - NCT03730922Recruiting
Delayed vs immediate breast reconstruction after mastectomy and radiation
This study compares two timing options for rebuilding the breast after mastectomy followed by radiation: a reconstruction done later (delayed) versus one done sooner (delayed-immediate). The goal is to see which approach works better and is safer for recovery after treatment.
AabenraaAges 18 years+ - NCT04261829Recruiting
Full method for breast reconstruction after mastectomy
This trial tests a “full breast reconstruction” approach for people who are planning or have had a breast removal (mastectomy). It may help improve how reconstruction is done and whether you can use the external expansion device as part of the process.
Maastricht, LimburgAges 18 years+ - NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT04714463Recruiting
Study on thoughts and body image during breast reconstruction
This study looks at how people’s expectations and body image feelings may affect experiences after breast reconstruction after mastectomy. It may help doctors understand what kinds of support or counseling could make recovery feel better.
GothenburgAges 18 years+ - NCT05490433Recruiting
Robot-assisted versus open nipple-sparing mastectomy with reconstruction
This trial compares two surgical approaches to remove the breast using a nipple-sparing mastectomy and do immediate breast reconstruction—either robot-assisted or open surgery. It aims to see how well each method works and how patients do afterward.
ChangwonAges 19–70
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Common questions
- Are there clinical trials for mastectomy and breast reconstruction?
- Yes. Clin2 currently lists 96 recruiting mastectomy and breast reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a mastectomy and breast reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a mastectomy and breast reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.