Clinical trials
Breast Reconstruction clinical trials
Below are recruiting breast reconstruction clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04345081Recruiting
Compare two breast surgery skin-sparing methods and recovery
This trial compares two types of mastectomy (with skin and nipple options) and implant reconstruction to see which gives better cosmetic results, comfort, and satisfaction. You may help doctors learn which approach leads to a better quality of life after surgery.
BudapestAges 18–65 - NCT04261829Recruiting
Full method for breast reconstruction after mastectomy
This trial tests a “full breast reconstruction” approach for people who are planning or have had a breast removal (mastectomy). It may help improve how reconstruction is done and whether you can use the external expansion device as part of the process.
Maastricht, LimburgAges 18 years+ - NCT05003635Recruiting
Testing a vacuum device to improve breast fat reconstruction
This trial tests whether an external vacuum device (EVEBRA) can help surgeons place fat grafts more effectively during breast reconstruction. You may be able to try the device in an office visit and, if you qualify, receive reconstruction using only your own fat.
Maastricht, LimburgAges 23–69 - NCT05833659Recruiting
Comparing two breast reconstruction positions after mastectomy
This trial compares two surgical techniques for breast reconstruction: placing the implant under the chest muscle versus in front of it. It may help people understand which approach works better for comfort and healing after mastectomy.
Beijing, Beijing MunicipalityAges 18–70 - NCT05888571Recruiting
Testing pre-chest breast reconstruction with or without mesh
This study looks at whether adding mesh (a supportive material) improves results in breast reconstruction placed in front of the chest. It may help some people heal better and get a more comfortable shape, but it depends on your surgery plan and health factors.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT06319157Recruiting
Minimal access vs. standard back muscle flap for breast reconstruction
This study compares a less invasive method of harvesting the latissimus dorsi (a back muscle) for breast reconstruction. It is for early-stage breast cancer patients who have mild to moderate breast sagging and want to use their own tissue for reconstruction.
Guangzhou, GuangdongAges 18–70 - NCT07798466Enrolling by invitation
Immediate breast reconstruction and radiation timing after breast cancer surgery
This trial studies whether getting radiation therapy right after breast reconstruction surgery is safe and effective for women with invasive breast cancer who had chemotherapy before surgery. It aims to improve outcomes and quality of life for patients needing both treatments.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07679594Recruiting
A study of Luna breast implants for augmentation or reconstruction
This study is testing Eurosilicone Luna breast implants in women who need breast augmentation (enlargement) or reconstruction after mastectomy. It aims to see how safe and effective the implants are over time.
Villefranche-sur-SaôneAges 18–65 - NCT07641985Recruiting
Fat grafting for breast reconstruction after cancer and radiation
This study compares two ways to rebuild the breast after mastectomy and radiation using your own tissue: fat grafting alone, or a more complex surgery using abdominal tissue. The goal is to see which method gives better results and quality of life.
Maastricht, LimburgAges 18 years+ - NCT07623564Enrolling by invitation
Breast Surgery Study Using Minimally Invasive Techniques
This study examines how well breast tissue is preserved during cosmetic breast augmentation or reconstruction using new minimally invasive surgical methods. If you're having one of these procedures, this research may help doctors better understand how to maintain healthy breast tissue and improve surgical outcomes.
Coyol, Alajuela ProvinceAges 18 years+ - NCT06728527Recruiting
Partial breast reconstruction with chest wall flap
This trial tests a specific type of partial breast reconstruction called a chest wall perforator flap. It's for women who previously had a lumpectomy and now want to improve the shape of their breast.
Cambridge, CambridgeshireAges 18 years+ - NCT04661501Recruiting
Trial of special breast skin graft in implant reconstruction
This trial studies whether a lab-made skin graft (called ADM) used with tissue expanders can improve breast reconstruction after mastectomy. It may help people who are planning a specific two-step implant reconstruction approach.
Vancouver, British ColumbiaAges 21–65 - NCT07546331Recruiting
Body Composition and Breast Reconstruction Outcomes
This study measures body composition (muscle and fat distribution) in patients undergoing breast reconstruction after mastectomy to understand how these measurements relate to surgical outcomes and recovery. Understanding these connections may help doctors better predict and optimize results for future patients.
San Francisco, CaliforniaAges 18 years+ - NCT07510698Recruiting
Same-day awake mastectomy with immediate breast reconstruction
This study tests whether people can have a mastectomy while awake (using numbing medicine instead of general anesthesia) and go home the same day with immediate breast reconstruction. It may be an option if you're healthy enough and have support at home.
Rome, RomeAges 18–75 - NCT03730922Recruiting
Delayed vs immediate breast reconstruction after mastectomy and radiation
This study compares two timing options for rebuilding the breast after mastectomy followed by radiation: a reconstruction done later (delayed) versus one done sooner (delayed-immediate). The goal is to see which approach works better and is safer for recovery after treatment.
AabenraaAges 18 years+ - NCT07365267Recruiting
3D printed mesh for breast reconstruction after mastectomy
This trial tests a new 3D printed biodegradable mesh used during breast reconstruction right after a mastectomy for breast cancer. It aims to see how well the mesh works for cosmetic results and safety.
Xi'an, ShaanxiAges 18–70 - NCT07352137Enrolling by invitation
Endoscopic Nipple-Sparing Mastectomy with Fat Grafting for Breast Reconstruction
This trial tests a new way to remove the breast through a small cut in the armpit (endoscopic nipple-sparing mastectomy) and immediately rebuild the breast using your own fat. It's for women with early-stage breast cancer who want to keep their nipple and have reconstruction at the same time.
Guanzhou, GuangdongAges 18–70 - NCT07331753Recruiting
Fat grafting with back muscle flap for breast reconstruction
This study tests if combining fat grafting with a muscle flap from the back improves breast reconstruction results after a mastectomy. It may help women who had a mastectomy and are now looking for delayed reconstruction.
Sohag, Sohag GovernorateAges 18 years+ - NCT05460780Recruiting
Tissue device study for breast reconstruction after mastectomy
This first-time-in-humans study tests a tissue-engineering chamber called MATTISSE® to help the healing of breast reconstruction using specific tissue flaps after mastectomy for cancer. If you qualify, you would be assessed for safety and how well the reconstructed tissue heals.
Strasbourg, FranceAges 18 years+ - NCT07230535Recruiting
Robotic vs standard mastectomy with DIEP reconstruction study
This trial compares how patients feel after open or robotic mastectomy combined with immediate DIEP flap reconstruction. It aims to see which approach improves wellbeing and recovery for women having this surgery.
BeaumontAges 18 years+ - NCT07209436Recruiting
Comparing two nerve blocks for implant-based breast reconstruction pain
This trial compares two types of nerve blocks (pectoral and paravertebral) to see which one provides better pain relief and physical recovery after immediate implant-based breast reconstruction. It is for adults having this surgery for the first time, either for treatment or prevention.
Boston, MassachusettsAges 18 years+ - NCT06930378Recruiting
Breast skin feeling after DIEP flap reconstruction
This trial compares three surgical techniques to see which one best preserves or improves skin feeling after breast reconstruction with a DIEP flap (using your own tissue to rebuild the breast). You may join if you are having this type of reconstruction and do not have nerve problems or smoke.
Geneva, Canton of GenevaAges 18–80 - NCT07135596Recruiting
OviTex PRS mesh for breast reconstruction after mastectomy
This study tests a special mesh called OviTex PRS used during immediate breast reconstruction after mastectomy. The goal is to see if it is safe and effective for supporting the new breast implant.
Tampa, FloridaAges 22–75 - NCT07084519RecruitingPhase 3
Short vs standard radiation after mastectomy with implant reconstruction
This trial compares standard radiation therapy to a shorter course (hypofractionated) for women who have had a mastectomy with implant reconstruction. The goal is to see if the shorter schedule works as well while possibly reducing side effects for the reconstructed breast.
Beijing, ProvinceAges 18–75
Hear when a new Breast Reconstruction trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Breast Reconstruction trials by city
Studies with a site in or near these metro areas.
Breast Reconstruction trials by state
Studies with a site anywhere in these states.
Common questions
- Are there clinical trials for breast reconstruction?
- Yes. Clin2 currently lists 110 recruiting breast reconstruction studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a breast reconstruction trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a breast reconstruction trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Breast Reconstruction After Mastectomy
- Implant Based Breast Reconstruction
- Mastectomy and Breast Reconstruction
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Breast Reconstruction Surgery
- DIEP Flap Breast Reconstruction
- Triple Negative Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.