Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,335 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06492759RecruitingPhase 2
High-dose radiation with pembrolizumab and chemo for pd-l1 positive tnbc
This trial tests giving high-dose radiation along with the immunotherapy drug pembrolizumab and chemo to people with a specific subtype of advanced breast cancer (PD-L1 positive triple negative). It may help shrink tumors and keep them from growing.
Atlanta, GeorgiaAges 18 years+ - NCT06493370RecruitingPhase 2
IV vitamin C plus chemo for bladder cancer
This trial tests adding high-dose vitamin C (ascorbate) to a standard chemotherapy combination for people with muscle-invasive bladder cancer who cannot take or choose not to take cisplatin. The goal is to find a more affordable and effective treatment option.
Iowa City, IowaAges 18 years+ - NCT06493760RecruitingPhase 2
Testing a new drug for advanced colorectal cancer
This trial tests a new drug called SSGJ-707 for people with colorectal cancer that has spread. It aims to see if the drug can help shrink or control the cancer.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06493864RecruitingPhase 1
BL-B16D1 for advanced breast cancer and solid tumors
This trial tests a new drug called BL-B16D1 for people with advanced breast cancer or other solid tumors that have not responded to standard treatments. The goal is to see if the drug is safe and how well it works.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT06494696Recruiting
PSMA PET/MRI with MRI for prostate cancer risk
This study tests whether a special scan (PSMA PET/MRI) combined with a standard MRI can better detect prostate cancer. It is for men who have not had a biopsy yet and are suspected of having prostate cancer.
Taoyuan CityAges 40–85 - NCT06495034Recruiting
Airwave compression to prevent arm swelling after breast cancer surgery
This trial tests whether wearing a special airwave compression sleeve after breast cancer surgery can prevent arm swelling (lymphedema). It is for women who are about to have lymph node surgery under their arm.
Shantou, GuangdongAges 18–70 - NCT06496373RecruitingEarly Phase 1
mRNA vaccine plus immunotherapy after pancreatic cancer surgery
This trial tests a personalized mRNA vaccine combined with an immunotherapy drug (PD-1 inhibitor) to prevent pancreatic cancer from returning after surgery. It is for patients whose tumors have specific genetic features and who cannot have standard chemotherapy.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06496490RecruitingPhase 2
TQB2102 for HER2-mutated non-small cell lung cancer
This trial tests a new drug, TQB2102, for people with advanced non-small cell lung cancer that has a specific change in the HER2 gene and has stopped responding to standard treatments. It aims to see if the drug can shrink or slow the cancer.
Fuzhou, FujianAges 18–75 - NCT06496724Recruiting
Study of albumin-bound paclitaxel combo for advanced breast cancer
This study tests a combination of two medicines (albumin-bound paclitaxel and a granulocyte-based therapy) for women with breast cancer that has come back or spread. It may be an option if you have already tried standard treatment and are looking for another approach.
Nanjing, JiangsuAges 18 years+ - NCT06498037RecruitingPhase 4
Better fentanyl dosing for cancer pain
This trial is testing a new way to give fentanyl under the skin for cancer-related pain. The goal is to find the right dose quickly and safely to make sure you get enough pain relief.
Rotterdam, South HollandAges 18–120 - NCT06497985RecruitingPhase 3
New drug combo for advanced colorectal cancer
This trial tests a combination of three drugs—tucidinostat, sintilimab, and bevacizumab—for people with a specific type of advanced colorectal cancer (MSS or pMMR) that has gotten worse after standard treatments. The goal is to see if this new mix can help shrink or slow the tumor.
Guangzhou, GuangdongAges 18–75 - NCT06498648RecruitingPhase 1/Phase 2
Abemaciclib with gemcitabine for soft tissue sarcoma
This trial tests whether adding the targeted drug abemaciclib to standard chemotherapy (gemcitabine) works better against certain soft tissue sarcomas. It is for people whose tumors have a normal Rb gene, which may help the drug work.
Houston, TexasAges 18 years+ - NCT06498479RecruitingPhase 3
Comparing a new drug to topotecan for relapsed small cell lung cancer
This trial tests a new drug called HS-20093 against a standard drug (topotecan) for people with small cell lung cancer that has returned after initial treatment. The goal is to see which drug works better.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06498388Recruiting
Predicting breast cancer with the BRAVE system
This trial is testing a new way to predict breast cancer risk using breast density from your recent mammogram. It may help people with a new breast finding and who haven't had prior breast procedures.
Sherbrooke, QuebecAges 18 years+ - NCT06498986RecruitingPhase 2
BL-B01D1 plus osimertinib for EGFR-mutant lung cancer
This trial tests a new drug (BL-B01D1) combined with osimertinib (Tagrisso) for people with advanced non-small cell lung cancer that has an EGFR mutation and who have not had any previous treatment. The goal is to see if the combination works better than standard care.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06500234RecruitingPhase 3
Nutrition and immunotherapy for cancer
This trial tests whether adding nutrition support helps cancer patients with malnutrition respond better to immunotherapy. You may be able to join if you have cancer and are malnourished, are generally active, and can swallow pills.
Qingdao, ShandongAges 18–80 - NCT06500312Recruiting
Lung cancer imaging and genetics study
This study looks at how CT scans of lung cancer can be linked to the tumor's biology and genetics. It aims to understand lung cancer better by combining imaging with lab results.
Wuhan, HubeiAges 18 years+ - NCT06501053Recruiting
Contact X-ray therapy for early rectal cancer
This trial tests a special type of contact X-ray (brachytherapy) for early-stage rectal cancer. It may help avoid major surgery by treating the tumor from inside the rectum.
Stockholm, SolnaAges 18 years+ - NCT06501261Recruiting
CALM therapy for advanced cancer patients in Chile
This study tests a type of talk therapy called CALM (Managing Cancer and Living Meaningfully) for people with advanced or metastatic cancer in Chile. The goal is to see if it helps with emotional well-being and coping.
Providencia, Santiago MetropolitanAges 18 years+ - NCT06502275Recruiting
Nutrition and Exercise for Older Colorectal Cancer Patients
This trial tests a nutrition and exercise program designed for older adults with colorectal cancer. It uses a smartphone app to help you stay active and eat well at home.
Chiayi CityAges 60 years+ - NCT06502691RecruitingPhase 1/Phase 2
New imaging test to measure PARP in metastatic breast cancer
This trial tests a new imaging scan called [18F]FTT PET that may show how much of a protein called PARP is in your tumors. This could help doctors decide if a PARP inhibitor (a type of targeted therapy) is right for you. You may be able to join if you have metastatic breast cancer and are already planning to take a PARP inhibitor.
Seattle, WashingtonAges 18 years+ - NCT06503432Recruiting
Does PD-L1 affect pain after lung cancer surgery?
This study looks at how a protein called PD-L1 relates to pain after lung cancer surgery. If you're having a VATS procedure, researchers want to see if PD-L1 levels affect your recovery and pain experience.
Beijing, Beijing MunicipalityAges 18–80 - NCT06503380Recruiting
Managing blood side effects from breast cancer targeted drugs
This study looks at how well current methods manage low blood cell counts (low platelets, low white blood cells, and low red blood cells) that can happen from targeted therapies for breast cancer. If you have breast cancer and are getting or have gotten a targeted therapy, this trial could help improve care for side effects like these.
Shanghai, Not US/CanadaAges Any age - NCT06503614RecruitingPhase 2
Durvalumab and monalizumab for early bladder cancer
This trial tests two drugs—durvalumab and monalizumab—for people with early-stage bladder cancer that hasn't spread into the muscle and has persisted or returned after BCG treatment. The goal is to see if this combination can control the cancer and delay or avoid the need for bladder removal surgery.
Tampa, FloridaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,335 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.