Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06574347RecruitingPhase 2
Two targeted drugs for EGFR-mutated, MET-high lung cancer
This trial tests a combination of two targeted drugs (vebreltinib and PLB1004) as the first treatment for people with a specific type of advanced lung cancer that has both an EGFR mutation and high MET protein. It may offer a new option for those who haven't had treatment yet.
Guangzhou, GuangdongAges 18 years+ - NCT06575452Recruiting
Using RNA modifications to diagnose and treat gliomas
This trial studies whether changes in RNA (the instructions inside cells) can help doctors better diagnose and treat gliomas, a type of brain tumor. If you are scheduled for surgery to remove a suspected glioma and have not had prior treatment, you may be able to join.
Montpellier, HéraultAges 18 years+ - NCT06576921RecruitingPhase 2
Study of serplulimab with chemo before surgery for stomach cancer
This trial tests if adding serplulimab to standard chemotherapy before surgery can help shrink locally advanced stomach or gastroesophageal junction cancer. It aims to improve treatment outcomes for patients who are candidates for surgery.
Shijiazhuang, Heibei ProvinceAges 18–75 - NCT06578052Recruiting
Irinotecan liposome with capecitabine for advanced pancreatic cancer
This trial tests a combination of two chemotherapy drugs (irinotecan liposome and capecitabine) for people with pancreatic cancer that has spread or cannot be removed by surgery and has gotten worse after initial treatment. The goal is to see if this combination can help slow the disease.
Shenzhen, GuangdongAges 18–80 - NCT06578637Recruiting
BHB supplement study for familial adenomatous polyposis
This trial tests whether taking a supplement called beta-hydroxybutyrate (BHB) can help prevent polyps in people with familial adenomatous polyposis (FAP), a condition that causes many polyps in the colon. The study has two parts: one for people who have already had colon surgery, and another for those who still have their colon.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06579196RecruitingPhase 1/Phase 2
Trabedersen with pembrolizumab for newly diagnosed advanced lung cancer
This trial tests a new drug, trabedersen, combined with the immunotherapy pembrolizumab for people with advanced non-small cell lung cancer that hasn't been treated yet. It's for patients whose tumors have a protein called PD-L1 (at least 1%) and who are generally well enough to participate.
Omaha, NebraskaAges 19 years+ - NCT06579248RecruitingEarly Phase 1
Cooling device to protect taste during radiation
This trial tests a special mouthpiece that cools the tongue during radiation therapy for advanced larynx cancer. It may help prevent taste loss caused by treatment.
Detroit, MichiganAges 18 years+ - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75 - NCT06579911Recruiting
Micro-ultrasound vs. MRI for prostate biopsy
This trial compares two advanced imaging techniques—high-frequency micro-ultrasound and multiparametric MRI—to guide biopsies for men who may have aggressive prostate cancer. The goal is to see which method better detects cancer while reducing unnecessary biopsies.
Salzburg, State of SalzburgAges 18–99 - NCT06581419RecruitingPhase 1/Phase 2
Testing IAP0971 in advanced solid tumors and lung cancer
This trial tests a new drug called IAP0971 for people with advanced solid tumors or a specific type of lung cancer. It may help if your cancer has not responded to other treatments or if you have PD-L1-positive lung cancer that hasn't been treated yet.
Beijing, Beijing MunicipalityAges 18–75 - NCT06581718Recruiting
Eye-tracking for endoscopy: a helpful new tool
This trial is testing whether eye-gaze technology can help doctors inspect the stomach and upper gut more thoroughly during a routine endoscopy. It may lead to fewer missed abnormalities.
London, LonodonAges 18 years+ - NCT06586242RecruitingPhase 2
Penpulimab, anlotinib, and chemo before surgery for esophageal cancer
This trial tests a combination of three drugs (penpulimab, anlotinib, and chemotherapy) given before surgery to shrink esophageal cancer. It is for people with locally advanced cancer who have not had treatment before.
Xi'an, Shaan'xiAges 18–75 - NCT06587295RecruitingPhase 1
ACM-CpG injection for advanced solid tumors that responded to immunotherapy before
This trial tests a new injection, ACM-CpG, for people with advanced or metastatic solid tumors that previously responded to immunotherapy (with or without chemotherapy) but later grew again. The goal is to see if ACM-CpG can help when other treatments have stopped working.
SingaporeAges 21–99 - NCT06589310Recruiting
Blood test for early cancer detection study
This study tests a blood test that looks for signs of cancer early in people without symptoms. It aims to see how well the test works in real-world settings.
Evanston, IllinoisAges 50–80 - NCT06589544Recruiting
Virtual reality and brain stimulation for depression in cancer patients
This trial tests whether combining virtual reality therapy with transcranial magnetic stimulation (a non-invasive brain treatment) can help reduce depression in people who have had cancer in the last 5 years. It aims to improve mood without using medication.
Ferrara, FEAges 18–100 - NCT06589609RecruitingPhase 1
FluBHPVE6E7 immunotherapy for HPV16-positive oropharyngeal cancer
This trial tests a new immunotherapy called FluBHPVE6E7 for people with HPV16-positive oropharyngeal cancer that has not spread to distant parts of the body. The treatment is given directly into the tumor to help the immune system fight the cancer.
ViennaAges 18–65 - NCT06590506Recruiting
Wearable health tracking for advanced solid tumor treatment
This trial studies how using a wearable device and smartphone app can help monitor your health during your first cancer treatment for advanced solid tumors. You will receive a known therapy (not a placebo), and the research team will collect real-world data to improve care.
A Coruña, A Coruña/ GaliciaAges 18 years+ - NCT06590948Recruiting
Using ultrasound features to classify liver nodules
This trial looks at whether special features seen on contrast-enhanced ultrasound can help doctors better classify liver nodules using a system called LI-RADS. It’s for people at high risk for liver cancer who have recent imaging and clear tissue diagnosis.
Hangzhou, ZhejiangAges 18 years+ - NCT06591039Recruiting
Breast cancer patient study in China
This study follows people diagnosed with breast cancer to learn more about the disease and treatment. It may help improve future care.
Shanghai, Shanghai MunicipalityAges Any age - NCT06592326RecruitingPhase 3
Study of 9MW2821 with toripalimab vs chemo for advanced bladder cancer
This trial is testing a new combination of two drugs (9MW2821 and toripalimab) against standard chemotherapy for people with advanced bladder cancer that has not been treated before. The goal is to see if this new approach works better at shrinking tumors or slowing the cancer's growth.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT06592573Recruiting
Anxiety and depression support for cancer caregivers
This trial tests whether online or in-person support can help reduce anxiety and depression symptoms in people caring for a loved one with cancer. You may be eligible if you're feeling anxious or down and are not currently in therapy.
Bologna, BOAges 18 years+ - NCT06593665RecruitingPhase 3
Morphine in spine vs. IV methadone for testicular cancer surgery pain
This trial compares two ways to manage pain after surgery for testicular cancer: a single injection of morphine into the spine (intrathecal morphine) vs. methadone given through an IV during surgery. The goal is to see which provides better pain relief and fewer side effects.
Indianapolis, IndianaAges 18–80 - NCT06594445RecruitingPhase 1
GTB-3650 TriKE for high-risk MDS and relapsed AML
This trial tests a new immunotherapy called GTB-3650 TriKE for people with high-risk MDS or AML that has come back or not responded to treatment. It aims to boost your immune system to fight the cancer.
Minneapolis, MinnesotaAges 18 years+ - NCT06595160Recruiting
Diet and gut bacteria in pancreatic cancer treatment
This study looks at how diet and the bacteria in your gut might affect how well chemotherapy works for pancreatic cancer that can be surgically removed. If you have been newly diagnosed with this type of pancreatic cancer, you may be able to join.
Atlanta, GeorgiaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,299 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.