Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,052 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06321081RecruitingPhase 2
Rechallenge combo for metastatic colorectal cancer
This trial tests a combination of three drugs (cetuximab, irinotecan, and envafolimab) as a ‘rechallenge’ – meaning if you had good results with cetuximab or irinotecan before, trying them again with a new drug might help shrink or control your cancer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06326190RecruitingPhase 2
Study of radioactive drug for recurrent meningioma
This trial tests a radioactive drug called 177Lu-DOTATATE for people with recurrent meningioma (a type of brain tumor) that has grown after surgery and radiation. The drug targets a protein on the tumor cells and delivers radiation directly to them.
InnsbruckAges 18 years+ - NCT06332755RecruitingPhase 1
Study of LB-LR1109 alone and with atezolizumab for cancer
This trial tests a new drug called LB-LR1109, alone or with atezolizumab, for adults with certain advanced solid tumors, including non-small cell lung cancer. It's for people whose cancer has worsened after standard treatments or who cannot have those treatments.
Fairfax, VirginiaAges 18 years+ - NCT06319963RecruitingPhase 1/Phase 2
Lenti-HPV-07 immunotherapy for HPV throat or cervical cancer
This trial tests a new immunotherapy called Lenti-HPV-07 for people with HPV-related throat or cervical cancer. It aims to help your immune system fight the cancer more effectively.
Orlando, FloridaAges 18 years+ - NCT05197881Recruiting
Daily adaptive radiation for newly diagnosed cervical cancer
This study tests a radiation plan that is adjusted day by day to better match your cervix and surrounding tissues during treatment. It’s for newly diagnosed, advanced cervical cancer patients who will receive standard pelvic radiation and chemotherapy.
Burmingham, AlabamaAges 18 years+ - NCT06320405RecruitingPhase 1/Phase 2
Combination therapy for advanced solid tumors
This trial tests a combination of three drugs—axatilimab, retifanlimab, and paclitaxel—for people with advanced solid tumors that have spread. It aims to see if this combination can shrink tumors or slow their growth, and it is for people who have already tried taxane chemotherapy.
Portland, OregonAges 18 years+ - NCT06320496Recruiting
Can a physical activity recovery stay help your child?
This study is for children age 8 to 18 who have a long-term health condition (like a chronic illness, rare disease, or disability) and are in a program to help them start being active again. The trial will check if a special exercise recovery stay helps them get stronger and feel better.
NancyAges 8–18 - NCT06333314RecruitingPhase 2
Dostarlimab for advanced dMMR/MSI cancers (not colorectal or endometrial)
This trial tests a drug called dostarlimab for people with certain advanced cancers that have a specific genetic feature (dMMR/MSI-H). The goal is to see if it helps shrink or control the cancer in people who haven't had other treatments yet.
AngersAges 18 years+ - NCT06335420Recruiting
Can carrot juice prevent colon polyps from coming back?
This study tests whether drinking carrot juice every day can lower the chance that large colon polyps or early colon cancers will come back. Researchers want to see if the nutrients in carrot juice help protect the lining of the colon.
OdenseAges 18 years+ - NCT06323044Recruiting
Support program for parents giving daily leukemia medicine
This study tests a support program that helps parents give their child's daily leukemia medicine (6-MP) on schedule and overcome any barriers. It aims to make it easier for families to stick with treatment.
Buffalo, New YorkAges Any age - NCT06337097Recruiting
Monitoring heart enzyme during immunotherapy
This study is for people starting immunotherapy with checkpoint inhibitors. It checks a heart enzyme (troponin) to see if the treatment affects your heart, so your doctor can monitor and manage any changes early.
Houston, TexasAges 18 years+ - NCT06320717Recruiting
AI-guided pre-surgery treatment for pancreatic cancer
This study tests how well an AI tool can guide which pre-surgery treatment is best for people with pancreatic cancer that can be removed. It uses your tumor's genetic fingerprint to choose the most effective therapy.
Buffalo, New YorkAges 18 years+ - NCT06327100RecruitingPhase 1/Phase 2
Tasquinimod for myelofibrosis after JAK inhibitor failure
This trial tests a new drug called tasquinimod, either alone or combined with ruxolitinib, for people with myelofibrosis. It's for patients who haven't gotten enough help from standard treatments or who can't take them.
Houston, TexasAges 18 years+ - NCT06327685RecruitingPhase 1
Avapritinib and Decitabine for SM-AHN
This trial tests a combination of two drugs, avapritinib and decitabine, for people with systemic mastocytosis plus another blood cancer (SM-AHN). The goal is to see if the combination works better than either drug alone.
Phoenix, ArizonaAges 18 years+ - NCT06336928Recruiting
Blood test validation for breast cancer diagnosis
This study is testing a new blood test (liquid biopsy) to see if it can accurately detect breast cancer or track remission. If you are a woman getting a mammogram, have an abnormal finding, were recently diagnosed, or are in remission after treatment, you may be able to join and help validate this test.
Los Angeles, CaliforniaAges 18 years+ - NCT06331468RecruitingPhase 2
Short-course radiation with chemo for advanced cervical cancer
This trial tests a shorter course of radiation combined with chemotherapy (hypofractionated radiochemotherapy) for women with advanced cervical cancer. It may help reduce treatment time while still effectively targeting the tumor.
Lexington, KentuckyAges 18–120 - NCT06336642RecruitingPhase 2
Personalized oxygen and support for cancer patients with shortness of breath
This trial tests a personalized oxygen and supportive care plan for cancer patients who are hospitalized and have shortness of breath at rest. It aims to find better ways to manage this symptom and improve comfort.
Houston, TexasAges 18 years+ - NCT06319378RecruitingPhase 2
Psilocybin for cancer-related depression
This trial tests whether a single dose of psilocybin, a psychedelic medication, can safely and effectively treat major depression in people with cancer. If you have cancer and have been feeling depressed for at least a month, you may qualify.
Gothenburg, GöteborgAges 20–80 - NCT06089421Recruiting
Genetic information assistant for cancer risk testing
This study tests a tool called GIA (Genetic Information Assistant) that helps people understand genetic testing for cancer risk. You would use the tool on a smartphone or computer during a genetic counseling session.
Charlottesville, VirginiaAges 18 years+ - NCT06317649RecruitingPhase 2
Venetoclax with hypomethylating agents for older or unfit adults with FLT3-mutated AML
This trial tests a combination of medicines (venetoclax and a hypomethylating agent) for people with acute myeloid leukemia (AML) who have a FLT3 mutation. It may be an option for older adults or those who cannot tolerate intensive chemotherapy.
Birmingham, AlabamaAges 18 years+ - NCT06311214RecruitingPhase 2
Personalized ADC therapy for advanced solid tumors
This trial tests personalized antibody-drug conjugates (ADCs) for advanced solid tumors. It looks for specific proteins on your tumor cells to match you with a treatment that targets them directly.
Duarte, CaliforniaAges 18 years+ - NCT06313801RecruitingPhase 2
Chemotherapy with or without PIPAC for stomach cancer
This trial tests whether adding a special type of chemotherapy sprayed directly into the abdomen (PIPAC) to standard chemotherapy is safer and works better for stomach cancer that has spread only to the lining of the abdomen.
Nizhny NovgorodAges 18–75 - NCT06295432RecruitingPhase 2
Study of two targeted drugs for EGFR-mutated lung cancer
This trial tests a combination of two targeted drugs (DZD9008 and AZD4205) for people with advanced non-small cell lung cancer that has a specific EGFR mutation and has stopped responding to standard treatments. The goal is to see if this combination can shrink tumors or slow cancer growth.
Guangzhou, GuangdongAges 18 years+ - NCT06312176RecruitingPhase 3
Study of new drugs for HR+/HER2- advanced breast cancer
This trial tests two new drugs (sacituzumab tirumotecan and pembrolizumab) against standard treatments for a type of advanced breast cancer that is hormone receptor positive and HER2 negative. It's for people whose cancer has worsened despite hormone therapy with a CDK4/6 inhibitor.
Chandler, ArizonaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,052 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.